CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26753
Family Name Serine/threonine-protein kinase Chk1 inhibitor SureCN6080935 family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00480112 Functional Category Bioactive
Superfamily Cannabinoid receptor 2 and Cannabinoid receptor 1 Binder Superfamily 56
Class Class 4242

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Gamma-aminobutyric acid A receptor Ligand Bromazepam Family 2 60
Hepatocyte growth factor receptor Ligand Arq 197 Family 10 400
Glycogen synthase kinase-3 beta and Protein kinase C beta type... 5 53
Cholecystokinin receptor type A Ligand Tarazepide Family 6 323
Poly [ADP-ribose] polymerase 1 Inhibitor AG-14699 Family 13 179
Growth hormone receptor Ligand EP-51216 Family 34 390
Protein kinase C alpha type and Protein kinase C beta type Inh... 16 86
Lethal factor Inhibitor GM6001 Family 50 435
Gamma-aminobutyric acid receptor subunit alpha-1 Ligand 1-(9h-... 4 25
Dihydroorotate dehydrogenase Inhibitor Nsc 665564 Family 2 83
Carbonic anhydrase 2 Inhibitor N-[2-(1h-indol-5-yl)-butyl]-4-s... 12 70
D(2) dopamine receptor and D(3) dopamine receptor Ligand 4-(4-... 3 15
Cyclin-dependent kinase 1 and Cyclin-dependent kinase 5 Inhibi... 2 5
Cyclin-dependent kinase 1 and G2/mitotic-specific cyclin-B1 In... 2 0
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Inosine-5'-monophosphate dehydrogenase 2 Inhibitor 1-methyl-1h... 24 50
Melanocortin receptor 3 and Melanocortin receptor 4 Ligand C[c... 20 18
5-hydroxytryptamine receptor 2C Ligand Cyclo[(6-bromotryptopha... 3 17
Cytochrome P450 11B1, mitochondrial and Aromatase Inhibitor 5-... 4 10
cAMP-specific 3',5'-cyclic phosphodiesterase 4A and cAMP-speci... 3 29
Endothelin B receptor Ligand IRL-2500 Family 34 87
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Histone deacetylase Inhibitor ST-5732 Family 8 6
Huntingtin and Glycogen synthase kinase-3 beta inhibitor SB 21... 2 4
Glycogen synthase kinase-3 beta and Protein kinase C alpha typ... 3 1
Glycogen synthase kinase-3 beta and Glycogen synthase kinase-3... 2 1
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 1 0
Sodium-dependent serotonin transporter and Sodium-dependent do... 10 2
Survival motor neuron protein and Nonstructural protein 1 inhi... 1 18
Serine/threonine-protein kinase D3 and Protein kinase C delta ... 3 0
Glycogen synthase kinase-3 beta and Tyrosine-protein kinase JA... 1 0
Glycogen synthase kinase-3 alpha and Glycogen synthase kinase-... 1 0
Glycogen synthase kinase-3 beta inhibitor 3-(2-bromoacetyl)-4-... 1 0
Sodium-dependent serotonin transporter and 5-hydroxytryptamine... 2 1
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 11 4
Substance-P receptor and Substance-K receptor ligand N-methyl-... 2 2
Sodium-dependent serotonin transporter and D(2) dopamine recep... 1 0
Protein-glutamine gamma-glutamyltransferase 2 inhibitor SureCN... 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00480112 CHEMBL238625 Bioactive SureCN6080935

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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