CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26766
Family Name Histone deacetylase 3 and Histone deacetylase 6 inhibitor (E)-3-(1'-benzyl-4-oxospiro[3H-1,3-benzoxazine-2,4'-piperidine]-6-yl)-N-hydroxyprop-2-enamide family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00480147 Functional Category Bioactive
Superfamily Cytochrome P450 2D6 and Delta-type opioid receptor Binder Superfamily
Class Class 216

Cousin Family NamesSeedsMembers
Sodium channel protein type 5 subunit alpha Ligand Flecainide ... 2 162
Cytochrome P450 2D6 and Delta-type opioid receptor Ligand 4-(s... 17 381
Potassium voltage-gated channel subfamily A member 3 Ligand 2-... 9 92
Histamine H3 receptor Ligand A-349821 Family 49 228
Melanin-concentrating hormone receptor 1 Ligand N-(1-benzylpip... 9 57
Voltage-dependent T-type calcium channel subunit alpha-1H Liga... 5 26
Kappa-type opioid receptor Ligand 3-(1-benzylpiperidin-4-yloxy... 24 54
D(2) dopamine receptor Ligand Epidepride Family 31 66
Acetylcholinesterase Inhibitor 6-methyl-4-(4-benzoylpiperazin-... 2 6
Alpha-2B adrenergic receptor and Alpha-2C adrenergic receptor ... 3 2
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 3 10
D(2) dopamine receptor and 5-hydroxytryptamine receptor 1A lig... 2 2
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 11 6
Orexin receptor type 1 and Orexin receptor type 2 ligand [(2S)... 3 1
Nociceptin receptor and Kappa-type opioid receptor ligand AGN-... 1 3
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 7 1
5-hydroxytryptamine receptor 3A and 5-hydroxytryptamine recept... 1 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00480147 CHEMBL2390999 Bioactive (E)-3-(1'-benzyl-4-oxospiro[3H-1,3-benzoxazine-2,4'-piperidine]-6-yl)-N-hydroxyprop-2-enamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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