CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26770
Family Name Rho-associated protein kinase 2 and Cytochrome P450 3A4 inhibitor 2-(4-bromophenyl)-2-hydroxy-1-[4-(1H-indazol-5-yl)piperazin-1-yl]ethanone family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00480167 Functional Category Bioactive
Superfamily Renin and Cytochrome P450 3A4 Binder Superfamily 3
Class Class 1301

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 3A Ligand Granisetron Family 26 212
Calcitonin gene-related peptide type 1 receptor and Cytochrome... 19 12
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand N-(1h... 2 12
Cytochrome P450 3A4 Inhibitor 5-(2-phenethylpiperazin-1-yl)-1h... 12 35
Rho-associated protein kinase 2 inhibitor AGN-PC-080M5E family 2 5
Serine/threonine-protein kinase 17A and Myosin light chain kin... 3 7
5-hydroxytryptamine receptor 1F and 5-hydroxytryptamine recept... 2 18
cAMP-dependent protein kinase catalytic subunit PRKX and Ribos... 1 2
cAMP-dependent protein kinase catalytic subunit PRKX and cGMP-... 1 3
Rho-associated protein kinase 1 and Ribosomal protein S6 kinas... 4 5
Histone deacetylase 1 inhibitor N-hydroxy-N',N'-bis[2-(1H-inda... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00480162 CHEMBL241271 Bioactive AGN-PC-014JKQ
CFAMM00480167 CHEMBL239150 Bioactive 2-(4-bromophenyl)-2-hydroxy-1-[4-(1H-indazol-5-yl)piperazin-1-yl]ethanone
CFAMM00480164 CHEMBL240867 Bioactive 2-amino-2-(4-bromophenyl)-1-[4-(1H-indazol-5-yl)piperazin-1-yl]ethanone

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27514 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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