CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26776
Family Name Sodium channel protein type 9 subunit alpha ligand SureCN12900177 family
No. of Seeds 9 No. of Other Members 8
Family Centroid CFAMM00480187 Functional Category Bioactive
Superfamily Melanocortin receptor 4 and Sodium channel protein type 9 subunit alpha Binder Superfamily
Class Class 2065

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
CGMP-inhibited 3',5'-cyclic phosphodiesterase Inhibitor Cilost... 6 202
Substance-K receptor Ligand MEN-14933 Family 13 154
Leukotriene A-4 hydrolase Inhibitor N5-[4-(4-(3-furyl)phenoxy)... 7 71
Substance-P receptor ligand N-[1-[acetyl-[(2-methoxyphenyl)met... 3 9
Cathepsin K inhibitor N-[(2S)-1-(4-methoxyanilino)propan-2-yl]... 11 10
Cathepsin K and Cathepsin L1 inhibitor 4-ethyl-N-[(2S)-1-[2-(4... 7 10
Melanocortin receptor 4 and Melanocortin receptor 5 ligand (2R... 8 9
Cathepsin S and Cathepsin K inhibitor SureCN3018173 family 2 4
Histone deacetylase 8 and Histone deacetylase 6 inhibitor (3S)... 4 16


External ID

Functional Category

Molecule Name

CFAMM00480187 CHEMBL2391644 Bioactive SureCN12900177
CFAMM00480175 CHEMBL253819 Bioactive tert-butyl N-[(2R)-1-[[(3R)-1-(cyclopropylmethyl)-4-oxo-5-(2,2,2-trifluoroethyl)-2,3-dihydro-1,5-benzodiazepin-3-yl]amino]-1-oxo-3-[2-(trifluoromethoxy)phenyl]propan-2-yl]carbamate
CFAMM00480186 CHEMBL2391645 Bioactive SureCN12900174
CFAMM00480180 CHEMBL247829 Bioactive tert-butyl N-[(2R)-1-oxo-1-[[(3S)-2-oxo-1-propan-2-yl-4,5-dihydro-3H-1-benzazepin-3-yl]amino]-3-[2-(trifluoromethoxy)phenyl]propan-2-yl]carbamate
CFAMM00480185 CHEMBL2391643 Bioactive tert-butyl N-[(2R)-1-[[(3R)-9-fluoro-2-oxo-1-propan-2-yl-4,5-dihydro-3H-1-benzazepin-3-yl]amino]-1-oxo-3-[2-(trifluoromethoxy)phenyl]propan-2-yl]carbamate
CFAMM00480179 CHEMBL247828 Bioactive SureCN1270247
CFAMM00480184 CHEMBL2391648 Bioactive SureCN12900175
CFAMM00480190 CHEMBL254928 Bioactive SureCN13310747
CFAMM00480183 CHEMBL2391649 Bioactive tert-butyl N-[(2R)-1-oxo-3-[2-(trifluoromethoxy)phenyl]-1-[[(3R)-6,7,9-trifluoro-2-oxo-1-propan-2-yl-4,5-dihydro-3H-1-benzazepin-3-yl]amino]propan-2-yl]carbamate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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