CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26809
Family Name Melanin-concentrating hormone receptor 1 ligand 1-[[4-(4-fluorophenyl)phenyl]methyl]-3-(1-hydroxy-2-methylpropan-2-yl)-1-[2-[1-[(4-methylphenyl)methyl]piperidin-4-yl]ethyl]urea family
No. of Seeds 2 No. of Other Members 10
Family Centroid CFAMM00480265 Functional Category Bioactive
Superfamily Melanin-concentrating hormone receptor 1 ligand 1-[[4-(4-fluorophenyl)phenyl]methyl]-3-(1-hydroxy-2-methylpropan-2-yl)-1-[2-[1-[(4-methylphenyl)methyl]piperidin-4-yl]ethyl]urea Superfamily
Class Class 5094

Cousin Family NamesSeedsMembers
Substance-P receptor Ligand Vestipitant Family 14 137
Bifunctional epoxide hydrolase 2 Inhibitor 1-adamantan-1-yl-3-... 11 6
Histamine H3 receptor Ligand N-benzyl-4-cyclopentylpiperazine-... 3 19
D(2) dopamine receptor and D(3) dopamine receptor Ligand ST-19... 5 27
Sodium-dependent serotonin transporter Inhibitor Irindalone Fa... 16 9
Pol polyprotein inhibitor (4R,5R,6S,7R)-1,3,4,7-tetrabenzyl-5,... 12 29
Muscarinic acetylcholine receptor M3 and Muscarinic receptor 3... 1 0
Pol polyprotein inhibitor AC1LADP4 family 2 0
Pol polyprotein inhibitor AC1LAH82 family 2 1
C-C chemokine receptor type 5 ligand AC1L9YPM family 3 6


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00480265 CHEMBL239871 Bioactive 1-[[4-(4-fluorophenyl)phenyl]methyl]-3-(1-hydroxy-2-methylpropan-2-yl)-1-[2-[1-[(4-methylphenyl)methyl]piperidin-4-yl]ethyl]urea
CFAMM00480262 CHEMBL392156 Bioactive 1-[[4-(3-cyanophenyl)phenyl]methyl]-3-(1-hydroxy-2-methylpropan-2-yl)-1-[2-[1-[(4-methylphenyl)methyl]piperidin-4-yl]ethyl]urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27639 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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