CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26811
Family Name Tyrosine-protein phosphatase non-receptor type 1 ligand 4-[4-[4-(2-benzyl-1-benzofuran-3-yl)phenyl]phenoxy]sulfonyl-2-hydroxybenzoic acid family
No. of Seeds 6 No. of Other Members 2
Family Centroid CFAMM00480280 Functional Category Bioactive
Superfamily Peroxisome proliferator-activated receptor gamma and Peroxisome proliferator-activated receptor alpha Ligand L-796449 Superfamily
Class Class 2126

Cousin Family NamesSeedsMembers
Retinoic acid receptor Ligand naphthoic acid derivative Adapal... 2 264
Estrogen receptor beta Ligand 2-(4-hydroxy-phenyl)benzofuran-5... 5 82
Aromatase and DNA-dependent protein kinase catalytic subunit I... 6 19
Oestrogen receptor and Estrogen receptor beta Ligand 7-chloro-... 2 27
3-oxo-5-alpha-steroid 4-dehydrogenase 1 and 3-oxo-5-alpha-ster... 9 81
Cytosolic phospholipase A2 Inhibitor [6,3''']biflavone Family 5 5
Creatine kinase Inhibitor 5-(4'-benzoylbiphenyl-4-yl)-2-furoic... 2 66
Retinoic acid receptor RXR-alpha and Peroxisome proliferator-a... 3 17
Tyrosine-protein phosphatase non-receptor type 1 ligand (2S)-2... 9 3


External ID

Functional Category

Molecule Name

CFAMM00480282 CHEMBL276983 Bioactive 4-[4-[4-(2-benzyl-1-benzofuran-3-yl)phenyl]phenoxy]sulfonylbenzoic acid
CFAMM00480280 CHEMBL23998 Bioactive 4-[4-[4-(2-benzyl-1-benzofuran-3-yl)phenyl]phenoxy]sulfonyl-2-hydroxybenzoic acid
CFAMM00480285 CHEMBL441959 Bioactive 5-[4-[4-(2-benzyl-1-benzofuran-3-yl)phenyl]phenoxy]sulfonyl-2-hydroxybenzoic acid
CFAMM00480277 CHEMBL24331 Bioactive 4-[4-[4-(2-benzyl-1-benzofuran-3-yl)phenyl]-2-cyclopentylphenoxy]sulfonyl-2-hydroxybenzoic acid
CFAMM00480284 CHEMBL24481 Bioactive 4-[4-[4-(2-benzoyl-1-benzofuran-3-yl)phenyl]-2-cyclopentylphenoxy]sulfonyl-2-hydroxybenzoic acid
CFAMM00480283 CHEMBL24524 Bioactive 4-[4-[4-(2-benzyl-1-benzofuran-3-yl)phenyl]-2,6-dimethylphenoxy]sulfonyl-2-hydroxybenzoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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