CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26816
Family Name Serine/threonine-protein kinase PLK2 and Serine/threonine-protein kinase PLK1 inhibitor (7R)-7-ethyl-5-methyl-8-(oxan-4-yl)-2-[5-(1,3-thiazol-2-yl)-1H-pyrazol-4-yl]-7H-pteridin-6-one family
No. of Seeds 3 No. of Other Members 0
Family Centroid CFAMM00480323 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A2a Binder Superfamily 21
Class Class 3494

Cousin Family NamesSeedsMembers
Aurora kinase A and Aurora kinase B inhibitor AGN-PC-09M6EM fa... 11 88


External ID

Functional Category

Molecule Name

CFAMM00480325 CHEMBL2402084 Bioactive (7R)-7-ethyl-5-methyl-8-[(3S)-oxolan-3-yl]-2-[5-(1,3-thiazol-2-yl)-1H-pyrazol-4-yl]-7H-pteridin-6-one
CFAMM00480324 CHEMBL2401964 Bioactive (7R)-7-ethyl-5-methyl-8-propan-2-yl-2-[5-(1,3-thiazol-2-yl)-1H-pyrazol-4-yl]-7H-pteridin-6-one
CFAMM00480323 CHEMBL2402083 Bioactive (7R)-7-ethyl-5-methyl-8-(oxan-4-yl)-2-[5-(1,3-thiazol-2-yl)-1H-pyrazol-4-yl]-7H-pteridin-6-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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