CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26830
Family Name Metabotropic glutamate receptor 5 ligand 2-(2-pyridin-3-ylethynyl)-6,7-dihydro-5H-[1,3]thiazolo[5,4-c]pyridin-4-one family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00480353 Functional Category Bioactive
Superfamily Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide Superfamily
Class Class 2536

Cousin Family NamesSeedsMembers
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Histone deacetylase 1 Inhibitor N-hydroxy-5-(pyridin-3-yl)thio... 9 46
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(2... 2 20
5-hydroxytryptamine receptor 1A and D(3) dopamine receptor lig... 2 8
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 13
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 16
Metabotropic glutamate receptor 1 and Metabotropic glutamate r... 8 4
Orexin receptor type 1 and Orexin receptor type 2 ligand N-[[(... 9 5
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 4 4
Metabotropic glutamate receptor 5 ligand 5-methyl-2-(2-phenyle... 2 5
Metabotropic glutamate receptor 5 ligand (2-methylcyclopropyl)... 3 6
C-C chemokine receptor type 5 and Potassium voltage-gated chan... 1 0
Gamma-aminobutyric acid receptor subunit alpha-2 and Gamma-ami... 6 4
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 7 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00480353 CHEMBL2403666 Bioactive 2-(2-pyridin-3-ylethynyl)-6,7-dihydro-5H-[1,3]thiazolo[5,4-c]pyridin-4-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27255 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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