CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26832
Family Name Neuropeptide Y receptor type 1 ligand [1-(4-chlorophenoxy)-9-[[(3R,4S)-3-fluoropiperidin-4-yl]methyl]carbazol-3-yl]-(4-methylpiperazin-1-yl)methanone family
No. of Seeds 5 No. of Other Members 7
Family Centroid CFAMM00480360 Functional Category Bioactive
Superfamily Neuropeptide Y receptor type 1 and Substance-P receptor Binder Superfamily
Class Class 4064

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Indomethacin Family 6 271
Arachidonate 5-lipoxygenase Inhibitor MK-591 Family 9 161
B2 bradykinin receptor Ligand FR-173657 Family 44 180
B2 bradykinin receptor ligand 4-[(E)-3-[[2-[2,4-dichloro-3-[[4... 29 2
D(3) dopamine receptor ligand N-[4-[4-(2,3-dichlorophenyl)pipe... 3 15
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 9
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand 18000... 1 1


External ID

Functional Category

Molecule Name

CFAMM00480364 CHEMBL411795 Bioactive [1-(4-chlorophenoxy)-9-(piperidin-4-ylmethyl)carbazol-3-yl]-(4-methylpiperazin-1-yl)methanone
CFAMM00480360 CHEMBL240404 Bioactive [1-(4-chlorophenoxy)-9-[[(3R,4S)-3-fluoropiperidin-4-yl]methyl]carbazol-3-yl]-(4-methylpiperazin-1-yl)methanone
CFAMM00480359 CHEMBL398782 Bioactive 1-(4-chlorophenoxy)-N-[2-(dimethylamino)ethyl]-9-[[(3S,4S)-3-fluoropiperidin-4-yl]methyl]carbazole-3-carboxamide
CFAMM00480358 CHEMBL438342 Bioactive [1-(4-chlorophenoxy)-9-[(5-fluoro-1,2,3,6-tetrahydropyridin-4-yl)methyl]carbazol-3-yl]-(4-methylpiperazin-1-yl)methanone
CFAMM00480366 CHEMBL392787 Bioactive [1-(4-chlorophenoxy)-9-[[(3S,4S)-3-fluoropiperidin-4-yl]methyl]carbazol-3-yl]-(4-methylpiperazin-1-yl)methanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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