CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26833
Family Name Tyrosine-protein kinase JAK3 and Activated CDC42 kinase 1 inhibitor AGN-PC-00E8IN family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00480367 Functional Category Bioactive
Superfamily Beta-3 adrenergic receptor and Pol polyprotein Binder Superfamily
Class Class 630

Cousin Family NamesSeedsMembers
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 37 265
5-hydroxytryptamine receptor 1B Ligand GR55562 Family 3 45
Serine/threonine-protein kinase Chk1 Inhibitor N-(5,6-diphenyl... 9 100
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
5-hydroxytryptamine receptor 2C Ligand N-(6-phenoxypyridin-3-y... 9 69
Disintegrin and metalloproteinase domain-containing protein 17... 2 8
Pol polyprotein inhibitor AC1LARNY family 28 17
Pol polyprotein inhibitor (2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-5... 12 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 2 19
MAP kinase-activated protein kinase 2 inhibitor CHEMBL1801290 ... 3 0
Renin inhibitor [2-(3-fluoro-2,6-dimethylphenoxy)-1-phenylpyrr... 5 12
Vascular endothelial growth factor receptor 1 and Receptor-typ... 2 11
Beta-3 adrenergic receptor ligand 6-[4-[2-[[(2S)-3-[(3,3-dimet... 6 7
Disintegrin and metalloproteinase domain-containing protein 17... 13 3
Activated CDC42 kinase 1 inhibitor 6-(4-methylsulfonylphenyl)-... 2 0
Activated CDC42 kinase 1 inhibitor 6-[4-(2-morpholin-4-ylethox... 7 1
Disintegrin and metalloproteinase domain-containing protein 17... 5 4
CGMP-dependent protein kinase inhibitor AGN-PC-075IHL family 2 8
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 1 3


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00480368 CHEMBL240430 Bioactive AGN-PC-00D3YG
CFAMM00480367 CHEMBL427687 Bioactive AGN-PC-00E8IN
CFAMM00480371 CHEMBL393596 Bioactive AGN-PC-00DJBE
CFAMM00480370 CHEMBL437754 Bioactive SureCN3565323

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

38989 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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