CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26850
Family Name Amine oxidase [flavin-containing] B and Metabotropic glutamate receptor 5 ligand 2-(4-chloroanilino)-7,7-dimethyl-6,8-dihydroquinazolin-5-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00480475 Functional Category Bioactive
Superfamily Thyrotropin receptor and Inositol monophosphatase 1 Binder Superfamily 2
Class Class 2174

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
Histone deacetylase 6 Inhibitor ACY-1215 Family 10 230
JAK Inhibitor Momelotinib Family 33 83
Tubulin beta chain Inhibitor 2-(3-chloro-phenyl)-1h-[1,8]napht... 3 13
Bifunctional epoxide hydrolase 2 Inhibitor 6-amino-n-(2,4-dich... 10 116
Cell division cycle 7-related protein kinase inhibitor pyrrolo... 4 10
Heat shock protein HSP 90-beta inhibitor 1-(2-amino-4-methylqu... 1 2
Protein kinase C theta type inhibitor (2-aminopyridin-3-yl)-[6... 4 1
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 2
5-hydroxytryptamine receptor 2A and D(2) dopamine receptor lig... 1 11
Transcription factor AP-1 and Nuclear factor NF-kappa-B p105 s... 2 4
Cannabinoid receptor 2 ligand SureCN13503317 family 7 7


External ID

Functional Category

Molecule Name

CFAMM00480474 CHEMBL2408568 Bioactive 2-(4-chloroanilino)-7-methyl-7,8-dihydro-6H-quinazolin-5-one
CFAMM00480475 CHEMBL2408563 Bioactive 2-(4-chloroanilino)-7,7-dimethyl-6,8-dihydroquinazolin-5-one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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