CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26851
Family Name Voltage-dependent L-type calcium channel subunit alpha-1C and Voltage-dependent L-type calcium channel subunit alpha-1D ligand 1-(6-chloro-4,4-diphenylpyrrolo[2,1-c][1,4]benzothiazin-1-yl)-N,N-dimethylmethanamine family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00480476 Functional Category Bioactive
Superfamily Prostaglandin D2 receptor 2 Ligand AZD1981 Superfamily
Class Class 1005

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 14 19
Translocator protein Inhibitor 5-phenyl-6-thia-10b-aza-benzo[e... 1 2
5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine recepto... 3 7
Sigma non-opioid intracellular receptor 1 ligand SureCN7434677... 1 0
Amyloid beta A4 protein and Luciferin 4-monooxygenase inhibito... 11 46


External ID

Functional Category

Molecule Name

CFAMM00480476 CHEMBL24086 Bioactive 1-(6-chloro-4,4-diphenylpyrrolo[2,1-c][1,4]benzothiazin-1-yl)-N,N-dimethylmethanamine
CFAMM00480477 CHEMBL26172 Bioactive 1-[4,4-diphenyl-8-(trifluoromethyl)pyrrolo[2,1-c][1,4]benzothiazin-1-yl]-N,N-dimethylmethanamine

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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