CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2686
Family Name Estrogen receptor and Estrogen receptor beta ligand SureCN5681592 family
No. of Seeds 7 No. of Other Members 3
Family Centroid CFAMM00336740 Functional Category Bioactive
Superfamily Estrogen receptor and Estrogen receptor beta Binder Superfamily
Class Class 833

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand Lasofoxifene Family 19 152
Squalene synthase Inhibitor (z)-3-[2-(9h-fluoren-2-yloxy)ethyl... 12 92
Leukotriene A-4 hydrolase Inhibitor N-benzyl-4-[(2r)-pyrrolidi... 6 40
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
Histamine H3 receptor and Sodium-dependent serotonin transport... 25 28
Cholesteryl ester transfer protein Inhibitor Tetrahydroquinoli... 3 8
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 9 79
D(2) dopamine receptor and D(3) dopamine receptor Ligand D-237... 21 56
Leukotriene A-4 hydrolase Inhibitor 1-[4-(4-iodophenoxy)phenyl... 5 18
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-00G... 16 4
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 14 12
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 3 2
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 8 0
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 2 8
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 11 9
Muscarinic acetylcholine receptor M3 and Muscarinic acetylchol... 4 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 15 1
Histamine H3 receptor and Sodium-dependent serotonin transport... 6 1
5-hydroxytryptamine receptor 7 ligand 1-(2-methoxyphenyl)-4-[2... 6 2
Histamine H3 receptor and Sodium-dependent serotonin transport... 2 1
D(2) dopamine receptor and Alpha-1B adrenergic receptor ligand... 2 2
Alpha-2A adrenergic receptor and Alpha-2C adrenergic receptor ... 2 26
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 0
Neuropeptide Y receptor type 5 ligand 3-[4-(4-fluorophenoxy)ph... 4 0
Estrogen receptor and Estrogen receptor beta ligand SureCN6716... 2 0
Estrogen receptor beta and Estrogen receptor ligand (E)-3-[4-(... 1 0
Estrogen receptor and Estrogen receptor beta ligand AGN-PC-00E... 1 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00336744 CHEMBL56390 Bioactive SureCN6931633
CFAMM00336743 CHEMBL58688 Bioactive SureCN5681653
CFAMM00336741 CHEMBL293297 Bioactive 2-(4-hydroxyphenyl)-1-[4-(2-piperidin-1-ylethoxy)phenyl]-3,4-dihydro-2H-quinolin-6-ol
CFAMM00336740 CHEMBL56198 Bioactive SureCN5681592
CFAMM00336746 CHEMBL56306 Bioactive AGN-PC-00F9YA
CFAMM00336739 CHEMBL60538 Bioactive SureCN5681903
CFAMM00336745 CHEMBL12987 Bioactive SureCN6278294

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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