CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26899
Family Name Prothrombin inhibitor N-[(2S)-3-(1,3-benzothiazol-2-yl)-1-[4-(2-fluoroethyl)piperidin-1-yl]-1-oxopropan-2-yl]-3,3-dimethyl-2,4-dihydro-1H-quinoline-8-sulfonamide family
No. of Seeds 10 No. of Other Members 15
Family Centroid CFAMM00480637 Functional Category Bioactive
Superfamily Prothrombin and Coagulation factor X Binder Superfamily 7
Class Class 2076

Cousin Family NamesSeedsMembers
Phosphoribosylaminoimidazolecarboxamide formyltransferase Inhi... 1 13
Prothrombin inhibitor methyl 2-[(2S)-5-(diaminomethylideneamin... 4 2
Dipeptidyl peptidase 4 and Dipeptidyl peptidase 8 inhibitor th... 1 3
Prothrombin inhibitor 6-[3-(4-acetylpiperazin-1-yl)-3-oxopropy... 4 1
Prothrombin inhibitor N-[(2S)-3-(1,3-benzothiazol-2-yl)-1-[4-(... 5 0
Fatty-acid amide hydrolase 1 inhibitor AGN-PC-04XJR1 family 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00480624 CHEMBL28277 Bioactive 1-[2-[1-[(2S)-3-(1,3-benzothiazol-2-yl)-2-[(3,3-dimethyl-2,4-dihydro-1H-quinolin-8-yl)sulfonylamino]propanoyl]piperidin-4-yl]ethyl]-3-methylurea
CFAMM00480637 CHEMBL286064 Bioactive N-[(2S)-3-(1,3-benzothiazol-2-yl)-1-[4-(2-fluoroethyl)piperidin-1-yl]-1-oxopropan-2-yl]-3,3-dimethyl-2,4-dihydro-1H-quinoline-8-sulfonamide
CFAMM00480623 CHEMBL422401 Bioactive N-[(2S)-3-(1,3-benzothiazol-2-yl)-1-[4-(2-hydroxyethyl)piperidin-1-yl]-1-oxopropan-2-yl]-3,3-dimethyl-2,4-dihydro-1H-quinoline-8-sulfonamide
CFAMM00480628 CHEMBL24933 Bioactive N-[(2S)-3-(1,3-benzothiazol-2-yl)-1-[4-(2-chloroethyl)piperidin-1-yl]-1-oxopropan-2-yl]-3,3-dimethyl-2,4-dihydro-1H-quinoline-8-sulfonamide
CFAMM00480634 CHEMBL28071 Bioactive methyl N-[2-[1-[(2S)-3-(1,3-benzothiazol-2-yl)-2-[(3,3-dimethyl-2,4-dihydro-1H-quinolin-8-yl)sulfonylamino]propanoyl]piperidin-4-yl]ethyl]carbamate
CFAMM00480640 CHEMBL412432 Bioactive 2-[8-[[(2S)-3-(1,3-benzothiazol-2-yl)-1-[4-(2-fluoroethyl)piperidin-1-yl]-1-oxopropan-2-yl]sulfamoyl]-3,3-dimethyl-2,4-dihydro-1H-quinolin-6-yl]ethylurea
CFAMM00480633 CHEMBL39086 Bioactive AGN-PC-073MJW
CFAMM00480626 CHEMBL27267 Bioactive 1-[2-[1-[(2S)-3-(1,3-benzothiazol-2-yl)-2-[(3,3-dimethyl-2,4-dihydro-1H-quinolin-8-yl)sulfonylamino]propanoyl]piperidin-4-yl]ethyl]-3-ethylurea
CFAMM00480645 CHEMBL24186 Bioactive 2-[1-[(2S)-3-(1,3-benzothiazol-2-yl)-2-[(3,3-dimethyl-2,4-dihydro-1H-quinolin-8-yl)sulfonylamino]propanoyl]piperidin-4-yl]ethyl N-methylcarbamate
CFAMM00480625 CHEMBL27268 Bioactive tert-butyl N-[2-[1-[(2S)-3-(1,3-benzothiazol-2-yl)-2-[(3,3-dimethyl-2,4-dihydro-1H-quinolin-8-yl)sulfonylamino]propanoyl]piperidin-4-yl]ethyl]carbamate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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