CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2690
Family Name Retinoic acid receptor RXR-alpha and Retinoic acid receptor RXR-beta ligand (2E,4E)-5-[3-[3,5-ditert-butyl-2-(3,3-difluoropropoxy)phenyl]thiophen-2-yl]-3-methylpenta-2,4-dienoic acid family
No. of Seeds 12 No. of Other Members 10
Family Centroid CFAMM00336780 Functional Category Bioactive
Superfamily Retinoic acid receptor RXR-alpha and Retinoic acid receptor RXR-beta ligand (2E,4E)-5-[3-[3,5-ditert-butyl-2-(3,3-difluoropropoxy)phenyl]thiophen-2-yl]-3-methylpenta-2,4-dienoic acid Superfamily
Class Class 3602

Cousin Family NamesSeedsMembers
Amyloid beta A4 protein Inhibitor 2,5-bis(4-methoxyphenyl)thio... 3 31
Aromatase Inhibitor NSC-122427 Family 1 0
Leukotriene B4 receptor 1 ligand AGN-PC-04XMB7 family 3 18
Prostaglandin E2 receptor EP3 subtype and D(2) dopamine recept... 2 24
Retinoic acid receptor gamma and Retinoic acid receptor alpha ... 1 5
Peroxisome proliferator-activated receptor alpha and Peroxisom... 1 7
Endothelin-1 receptor and Endothelin B receptor ligand AGN-PC-... 4 12
Peroxisome proliferator-activated receptor delta and Peroxisom... 4 5
Prostaglandin E2 receptor EP1 subtype and Thromboxane A2 recep... 1 9
Tyrosine-protein phosphatase non-receptor type 1 ligand 2-[4-[... 12 9
DNA-(apurinic or apyrimidinic site) lyase and Phospholipase A2... 1 4
Progesterone receptor ligand 6-(5-chlorothiophen-2-yl)chromen-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00336785 CHEMBL131561 Bioactive (2E,4E)-5-[3-[2-(3-fluoropropoxy)-3,5-di(propan-2-yl)phenyl]thiophen-2-yl]-3-methylpenta-2,4-dienoic acid
CFAMM00336772 CHEMBL129887 Bioactive (2E,4E)-5-[3-[3-tert-butyl-2-(2,2-difluoroethoxy)-5-ethylphenyl]thiophen-2-yl]-3-methylpenta-2,4-dienoic acid
CFAMM00336778 CHEMBL43238 Bioactive SureCN14203233
CFAMM00336783 CHEMBL340555 Bioactive (2E,4E)-5-[3-[2-(2,2-difluoroethoxy)-3,5-di(propan-2-yl)phenyl]thiophen-2-yl]-3-methylpenta-2,4-dienoic acid
CFAMM00336782 CHEMBL41260 Bioactive SureCN6828619
CFAMM00336788 CHEMBL291034 Bioactive (E)-3-[4-(3,5-ditert-butyl-2-heptoxyphenyl)-1-benzothiophen-2-yl]but-2-enoic acid
CFAMM00336776 CHEMBL130374 Bioactive (2E,4E,6Z)-7-[2-(2,2-difluoroethoxy)-3-propan-2-yl-5-thiophen-2-ylphenyl]-3-methylocta-2,4,6-trienoic acid
CFAMM00336781 CHEMBL41890 Bioactive SureCN1073066
CFAMM00336775 CHEMBL339298 Bioactive (2E,4E)-5-[3-[3-tert-butyl-5-ethyl-2-(3-fluoropropoxy)phenyl]thiophen-2-yl]-3-methylpenta-2,4-dienoic acid
CFAMM00336780 CHEMBL335762 Bioactive (2E,4E)-5-[3-[3,5-ditert-butyl-2-(3,3-difluoropropoxy)phenyl]thiophen-2-yl]-3-methylpenta-2,4-dienoic acid
CFAMM00336786 CHEMBL41146 Bioactive (E)-3-[4-[3,5-ditert-butyl-2-(3-fluoropropoxy)phenyl]-1-benzothiophen-2-yl]but-2-enoic acid
CFAMM00336774 CHEMBL132488 Bioactive (2E,4E)-5-[3-[3,5-di(propan-2-yl)-2-(2,2,2-trifluoroethoxy)phenyl]thiophen-2-yl]-3-methylpenta-2,4-dienoic acid

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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