CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26909
Family Name Mineralocorticoid receptor and Glucocorticoid receptor ligand 8-chloro-6-[4-(4-fluorophenyl)-2-methyl-5-oxo-1,2-dihydropyrrol-3-yl]-4H-1,4-benzoxazin-3-one family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00480676 Functional Category Bioactive
Superfamily D(4) dopamine receptor and D(3) dopamine receptor Binder Superfamily 2
Class Class 1458

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1A Ligand (s)-way 100135 Family 94 975
Muscarinic acetylcholine receptor M1 Ligand AC-260584 Family 4 36
Alpha-2C adrenergic receptor Ligand ARC239 Family 15 23
5-hydroxytryptamine receptor 1A Ligand NAN-190 Family 14 28
5-hydroxytryptamine receptor 1A and Alpha-1A adrenergic recept... 18 12
Alpha-1A adrenergic receptor and Alpha-1B adrenergic receptor ... 6 23
Substance-K receptor Ligand MEN-14933 Family 13 154
Alpha-1A adrenergic receptor Ligand Upidosin Family 8 46
Alpha-1A adrenergic receptor and D(2) dopamine receptor Ligand... 5 49
Leukotriene A-4 hydrolase Inhibitor N5-[4-(2-oxo-3-phenylpropo... 1 61
Macrophage migration inhibitory factor Inhibitor Benzofuran-2-... 5 67
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
Reverse transcriptase Inhibitor 10-propyl-10h-dibenzo[b,f][1,4... 9 60
D(2) dopamine receptor ligand 7-[4-[4-(2-ethoxyphenyl)piperazi... 12 14
Coagulation factor X and Trypsin-1 inhibitor AGN-PC-01ZLS4 family 2 8
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 4 4
D(4) dopamine receptor and D(2) dopamine receptor ligand SureC... 4 3
D(4) dopamine receptor and D(3) dopamine receptor ligand SureC... 5 0
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor lig... 5 2
Androgen receptor ligand (2R)-2-ethyl-1-(2,2,2-trifluoroethyl)... 32 6
Potassium voltage-gated channel subfamily H member 2 and Melan... 5 4
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 11 8
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 1 0
Arachidonate 5-lipoxygenase inhibitor ethyl (E)-3-(10H-phenoxa... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00480675 CHEMBL2419301 Bioactive 6-[4-(4-fluorophenyl)-2-methyl-5-oxo-1,2-dihydropyrrol-3-yl]-8-methyl-4H-1,4-benzoxazin-3-one
CFAMM00480676 CHEMBL2419300 Bioactive 8-chloro-6-[4-(4-fluorophenyl)-2-methyl-5-oxo-1,2-dihydropyrrol-3-yl]-4H-1,4-benzoxazin-3-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

26232 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543