CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26955
Family Name Glucokinase inhibitor 4-methyl-N-[3-phenylmethoxy-5-(pyridin-2-ylmethylsulfanyl)pyridin-2-yl]-1,3-thiazol-2-amine family
No. of Seeds 1 No. of Other Members 8
Family Centroid CFAMM00480839 Functional Category Bioactive
Superfamily Glucokinase and cAMP Binder Superfamily
Class Class 834

Cousin Family NamesSeedsMembers
Serine/threonine-protein kinase Chk1 and Serine/threonine-prot... 23 121
SB1518 family 7 103
Tissue-type plasminogen activator Inhibitor N-(7-benzyloxy-iso... 4 37
Metabotropic glutamate receptor 5 Ligand (3-ethoxy-pyridin-2-y... 3 12
Peptidyl-prolyl cis-trans isomerase A Inhibitor 3-[3-(3-benzyl... 3 34
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 17 49
Metabotropic glutamate receptor 5 Ligand 7-(3,5-dimethoxypheny... 2 7
Rho-associated protein kinase 2 inhibitor SureCN13457044 family 1 17
Adenosine kinase inhibitor 5-[3-(4-methoxyphenyl)propyl]-6-[2-... 2 11
Aurora kinase A inhibitor AGN-PC-00BCUF family 16 43
Inositol monophosphatase 1 and Microtubule-associated protein ... 1 12
Dihydrofolate reductase inhibitor AC1LA5HU family 8 4
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 5 6
P2Y purinoceptor 1 inhibitor N-[2-(2-tert-butylphenoxy)pyridin... 6 3
Adenosine receptor A2a and Adenosine receptor A1 ligand 2-(3-c... 3 3
TGF-beta receptor type-1 ligand SureCN373216 family 3 14
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 4 3
Potassium-transporting ATPase alpha chain 1 and Potassium-tran... 2 11
Urokinase-type plasminogen activator inhibitor AGN-PC-01XMBP f... 3 7
Sodium channel protein type 5 subunit alpha and Sodium channel... 15 8
Corticotropin-releasing factor receptor 1 ligand N-[(1R,2S)-2-... 3 0
Cysteinyl leukotriene receptor 1 and Platelet-activating facto... 1 1
Sonic hedgehog protein and DNA polymerase beta inhibitor STK13... 1 0
Nuclear receptor ROR-gamma and Neuropeptide S receptor ligand ... 1 0
TGF-beta receptor type-1 ligand 2wou family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00480839 CHEMBL2430860 Bioactive 4-methyl-N-[3-phenylmethoxy-5-(pyridin-2-ylmethylsulfanyl)pyridin-2-yl]-1,3-thiazol-2-amine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27075 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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