CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26957
Family Name 5-hydroxytryptamine receptor 7 and 5-hydroxytryptamine receptor 1A ligand 2-[4-(2-quinolin-8-yloxyethylamino)butyl]-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazole-1,3-dione;hydrochloride family
No. of Seeds 1 No. of Other Members 1
Family Centroid CFAMM00480846 Functional Category Bioactive with Natural Product
Superfamily Nischarin and Cathepsin K Binder Superfamily
Class Class 3208

Cousin Family NamesSeedsMembers
Melatonin receptor type 1A Ligand Melatonin Family 20 988
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor indole... 28 2712
ostatin receptor 5 Ligand Pasireotide Diaspartate Family 11 151
Protein kinase C theta type Inhibitor 4-(1h-indol-5-yloxy)-5-s... 21 194
Serine/threonine-protein kinase Chk1 Inhibitor A-432411 Family 4 70
5-hydroxytryptamine receptor 2A and Amine oxidase [flavin-cont... 4 32
Arachidonate 5-lipoxygenase Inhibitor TZI-41127 Family 7 34
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 18 72
Cannabinoid receptor 1 Ligand 1-(2-morpholinoethyl)-1h-indol-3... 8 46
Melatonin receptor type 1B and Melatonin receptor type 1A liga... 3 16
Disintegrin and metalloproteinase domain-containing protein 17... 14 9
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 2 6
Translocator protein inhibitor SureCN13502542 family 20 2
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 48
Receptor-type tyrosine-protein kinase FLT3 and Mast/stem cell ... 3 5
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 2 5
Histamine H3 receptor ligand AGN-PC-00BG7Z family 11 49
Disintegrin and metalloproteinase domain-containing protein 17... 4 1
Cellular tumor antigen p53 and DNA polymerase beta inhibitor C... 1 15
Translocator protein inhibitor N-methyl-2-(2-oxo-5-pyridin-4-y... 8 15
Seprase and Prolyl endopeptidase inhibitor N-[2-[(2S)-2-cyanop... 1 3
Proto-oncogene tyrosine-protein kinase receptor Ret and Vascul... 5 14
Orexin receptor type 2 and Orexin receptor type 1 ligand 9-(4,... 2 5
Matrix metalloproteinase-9 and Neutrophil collagenase inhibito... 3 7
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor CHEMBL4... 6 2
B2 bradykinin receptor and Cytochrome P450 3A4 ligand SureCN15... 4 0
Platelet-activating factor receptor ligand (7-phenylmethoxy-1H... 1 1
Nischarin inhibitor SureCN7810370 family 1 0
Caspase-3 and Caspase-7 inhibitor (2S)-N-[(3S)-2-hydroxy-5-oxo... 4 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00480846 CHEMBL2431041 Bioactive 2-[4-(2-quinolin-8-yloxyethylamino)butyl]-5,6,7,7a-tetrahydropyrrolo[1,2-c]imidazole-1,3-dione;hydrochloride

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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