CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26965
Family Name Metabotropic glutamate receptor 5 ligand N-[(2R)-3-hydroxy-3-methylbutan-2-yl]-5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine-2-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00480868 Functional Category Bioactive
Superfamily Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(2-amino-5-(thiophen-2-yl)phenyl)nicotinamide Superfamily
Class Class 2536

Cousin Family NamesSeedsMembers
Cathepsin B and Cathepsin K Inhibitor L-006235-1 Family 19 75
Histamine H3 receptor ligand SureCN1857507 family 1 4
Neuronal acetylcholine receptor subunit alpha-7 ligand AGN-PC-... 7 1
Delta-type opioid receptor and Mu-type opioid receptor ligand ... 9 16
Cyclin-dependent kinase 5 and Cyclin-dependent kinase 5 activa... 4 4
Metabotropic glutamate receptor 5 ligand AGN-PC-09SALK family 2 15
Gamma-aminobutyric acid receptor subunit alpha-2 and Gamma-ami... 6 4


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00480868 CHEMBL2431202 Bioactive N-[(2R)-3-hydroxy-3-methylbutan-2-yl]-5-[2-(2-methyl-1,3-thiazol-4-yl)ethynyl]pyridine-2-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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