CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26973
Family Name Histone deacetylase 6 and Histone deacetylase 8 inhibitor N-hydroxy-2-(1-methylpyrrole-2-carbonyl)-1,3-dihydroisoindole-5-carboxamide family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00480884 Functional Category Bioactive
Superfamily MO15-related protein kinase Pfmrk Inhibitor (e)-1-(4-nitro-phenyl)-3-pyridin-2-yl-propenone Superfamily
Class Class 1284

Cousin Family NamesSeedsMembers
Cytochrome P450 11B1, mitochondrial Inhibitor Metyrapone Family 9 243
SUR2-type K(ATP) channel Ligand Nicorandil Family 5 85
Prothrombin Inhibitor Ximelegatran Family 8 157
Mitogen-activated protein kinase 14 Inhibitor Losmapimod Family 5 154
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Substance-P receptor Ligand TAK-637 Family 18 63
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
Cannabinoid receptor 2 Ligand JWH-167 Family 25 168
Poly [ADP-ribose] polymerase 1 Inhibitor 1,7,8,9-tetrahydro-1,... 19 64
Transient receptor potential cation channel subfamily V member... 6 23
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-3... 37 1
Cannabinoid receptor 1 and Cannabinoid receptor 2 Ligand JWH-2... 8 1
D(4) dopamine receptor Ligand ABT-670 Family 4 14
Delta-type opioid receptor Ligand H-poa-ser-gly-phe-leu-thr-oh... 5 12
Bifunctional epoxide hydrolase 2 Inhibitor N-(3,3-diphenyl-pro... 6 14
Amine oxidase [flavin-containing] A Inhibitor N-benzyl-1h-pyrr... 12 46
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Vasopressin V2 receptor Ligand YM-35278 Family 33 38
Aldose reductase Inhibitor 3-(3-benzoyl-1h-pyrrol-1-yl)propano... 3 7
Survival motor neuron protein and Beta-lactamase inhibitor CHE... 1 0
Disintegrin and metalloproteinase domain-containing protein 17... 2 11
Peptide deformylase inhibitor (2R)-N-[(2S)-3,3-dimethyl-1-oxo-... 2 1
Histamine H3 receptor ligand SureCN1857507 family 1 4
Amine oxidase [flavin-containing] A and Amine oxidase [flavin-... 3 12
Serine/threonine-protein kinase PLK1 and MAP kinase-activated ... 1 2
Histone deacetylase 6 and Histone deacetylase 1 inhibitor 4-[(... 3 5
RAC-beta serine/threonine-protein kinase and 3-phosphoinositid... 11 4
Metabotropic glutamate receptor 5 ligand AGN-PC-09SALK family 2 15
Histone deacetylase 1 inhibitor (2S)-N'-hydroxy-2-(pyridine-2-... 3 0
D(3) dopamine receptor and D(2) dopamine receptor ligand (7S)-... 2 19
Substance-P receptor and Substance-K receptor ligand N-methyl-... 2 2
72 kDa type IV collagenase and Interstitial collagenase inhibi... 1 1
Tyrosyl-DNA phosphodiesterase 1 and Huntingtin inhibitor CHEMB... 1 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00480884 CHEMBL2431906 Bioactive N-hydroxy-2-(1-methylpyrrole-2-carbonyl)-1,3-dihydroisoindole-5-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27521 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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