CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26989
Family Name cGMP-specific 3',5'-cyclic phosphodiesterase and Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A inhibitor methyl 3-[4-(2-hydroxyethyl)piperazine-1-carbonyl]-6,7-dimethoxy-1-(3,4,5-trimethoxyphenyl)naphthalene-2-carboxylate family
No. of Seeds 1 No. of Other Members 5
Family Centroid CFAMM00480919 Functional Category Bioactive
Superfamily Heat shock protein 90, putative Inhibitor KW-2478 Superfamily
Class Class 727

Cousin Family NamesSeedsMembers
Kappa-type opioid receptor Ligand Fedotozine Family 1 11
Histamine H3 receptor Ligand A-349821 Family 49 228
Histamine H1 receptor Ligand MDL-105212 Family 16 56
Ribosyldihydronicotinamide dehydrogenase [quinone] Inhibitor N... 2 6
Glycine receptor subunit beta Ligand ORG-25543 Family 10 153
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor 2-[3-[(1R... 9 46
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL14038... 1 9
Prelamin-A/C and Retinal dehydrogenase 1 inhibitor CHEMBL15810... 1 1
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor AGN-PC-00... 5 14
Peptidyl-prolyl cis-trans isomerase FKBP1A inhibitor Tetracycl... 1 1
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor SureCN7... 1 1
NP ((1r,4as,8as)-4a-hydroxy-1-(3,4,5-trimethoxyphenyl)octahydr... 3 3
(1R,5S)-3-(2-(3,4,5-trimethoxyphenyl)acetyl)-3,4,5,6-tetrahydr... 2 0
2-(2,4-dimethoxyphenyl)-2,3,6,7,11,12-hexahydro-[1,4]dioxepino... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00480919 CHEMBL24385 Bioactive methyl 3-[4-(2-hydroxyethyl)piperazine-1-carbonyl]-6,7-dimethoxy-1-(3,4,5-trimethoxyphenyl)naphthalene-2-carboxylate

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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