CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM26994
Family Name Diacylglycerol O-acyltransferase 1 inhibitor ethyl 4-[5-[[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carbonyl]amino]pyridin-2-yl]piperazine-1-carboxylate family
No. of Seeds 5 No. of Other Members 8
Family Centroid CFAMM00480941 Functional Category Bioactive
Superfamily Prelamin-A/C and Diacylglycerol O-acyltransferase 1 Binder Superfamily
Class Class 5354

Cousin Family NamesSeedsMembers
Adenosine receptor A1 and Adenosine receptor A2a Ligand N-(2-(... 21 108
Adenosine receptor A2b and Adenosine receptor A2a ligand AGN-P... 2 0
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic ... 5 12
Prothrombin inhibitor SureCN6925359 family 6 18
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 2 6
Diacylglycerol O-acyltransferase 1 inhibitor SureCN2789698 family 2 8
Diacylglycerol O-acyltransferase 1 inhibitor 3-[[1-[5-[[2-(3-m... 1 1
Diacylglycerol O-acyltransferase 1 and Cytochrome P450 3A4 inh... 3 1


External ID

Functional Category

Molecule Name

CFAMM00480946 CHEMBL2441201 Bioactive cyclopentyl 4-[5-[[2-piperidin-1-yl-4-(trifluoromethyl)-1,3-oxazole-5-carbonyl]amino]pyridin-2-yl]piperazine-1-carboxylate
CFAMM00480944 CHEMBL2441020 Bioactive ethyl 1-[5-[[2-(2-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carbonyl]amino]pyridin-2-yl]piperidine-4-carboxylate
CFAMM00480942 CHEMBL2441019 Bioactive ethyl 1-[5-[[2-piperidin-1-yl-4-(trifluoromethyl)-1,3-oxazole-5-carbonyl]amino]pyridin-2-yl]piperidine-4-carboxylate
CFAMM00480941 CHEMBL2441024 Bioactive ethyl 4-[5-[[2-(3-methylpiperidin-1-yl)-4-(trifluoromethyl)-1,3-oxazole-5-carbonyl]amino]pyridin-2-yl]piperazine-1-carboxylate
CFAMM00480947 CHEMBL2441200 Bioactive propan-2-yl 4-[5-[[2-piperidin-1-yl-4-(trifluoromethyl)-1,3-oxazole-5-carbonyl]amino]pyridin-2-yl]piperazine-1-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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