CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

Family Name C-C chemokine receptor type 5 ligand AC1L9U8N family
No. of Seeds 8 No. of Other Members 6
Family Centroid CFAMM00306109 Functional Category Bioactive
Superfamily C-C chemokine receptor type 5 Binder Superfamily 2
Class Class 238

Cousin Family NamesSeedsMembers
Sodium-dependent dopamine transporter inhibitor substituted ph... 22 416
Alpha-2 adrenergic receptor ligand opiate Meperidine Family 13 76
Histamine H1 receptor Ligand Levocabastine Family 1 1
Muscarinic acetylcholine receptor M5 ligand Tropane alkaloid A... 18 12
Angiotensin-converting enzyme Inhibitor Quinapril Family 3 105
Angiotensin-converting enzyme and Neprilysin Inhibitor M100,24... 18 60
C-C chemokine receptor type 5 ligand AC1L9U85 family 1 1
C-C chemokine receptor type 5 ligand (2R)-3-cyclopropyl-2-[(3S... 10 4
C-C chemokine receptor type 5 ligand (2R)-3-cyclobutyl-2-[(3S,... 10 0
3-oxo-5-alpha-steroid 4-dehydrogenase 2 inhibitor 2-[4-[[1-(2,... 2 7
Leukotriene B4 receptor 1 and Leukotriene B4 receptor 2 ligand... 3 13
C-C chemokine receptor type 5 ligand (2R)-2-[(3S,4S)-3-(3-fluo... 7 0
C-C chemokine receptor type 5 ligand (2R)-3-cyclopropyl-2-[(3S... 6 0
C-C chemokine receptor type 5 ligand (2R)-2-[(3S,4S)-3-[[4-[3,... 3 0
Type-2 angiotensin II receptor ligand SureCN3515167 family 2 0
C-C chemokine receptor type 5 ligand AC1LAX0N family 2 0


External ID

Functional Category

Molecule Name

CFAMM00306117 CHEMBL101961 Bioactive AC1L9U8Q
CFAMM00306109 CHEMBL100596 Bioactive AC1L9U8N
CFAMM00306108 CHEMBL99788 Bioactive methyl (2R)-2-cyclohexyl-2-[(3S,4S)-3-[[4-hydroxy-4-(3-phenylpropyl)piperidin-1-yl]methyl]-4-phenylpyrrolidin-1-yl]acetate
CFAMM00306115 CHEMBL100958 Bioactive AC1L9U8K
CFAMM00306107 CHEMBL432596 Bioactive AC1LAX0R
CFAMM00306105 CHEMBL322603 Bioactive AC1L9U8B
CFAMM00306111 CHEMBL100336 Bioactive AC1LAX0T
CFAMM00306104 CHEMBL320149 Bioactive AC1LAX0V

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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