CFam Chemical Families Database
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Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM270
Family Name Gamma-aminobutyric acid receptor subunit pi and GABA theta subunit ligand 8-chloro-2-phenyl-1H-pyrazolo[4,3-c]quinolin-3-one family
No. of Seeds 9 No. of Other Members 22
Family Centroid CFAMM00246341 Functional Category Bioactive
Superfamily Glucocorticoid receptor Ligand 1-(3-chloro-4-fluorophenyl)-2,2,2-trifluoro-1-(1-(4-fluorophenyl)-1h-indazol-5-y L)ethanol (enantiomeric Mix) Superfamily
Class Class 1734

Cousin Family NamesSeedsMembers
D(4) dopamine receptor Ligand Fauc 113 Family 14 96
Adenosine receptor A3 Ligand 4-methoxy-2-phenyl-2h-pyrazolo[4,... 9 49
Glucocorticoid receptor Ligand 1-(3-chloro-4-fluorophenyl)-2,2... 1 13
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 4 0
Gamma-aminobutyric acid receptor subunit gamma-2 and Gamma-ami... 8 10
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 6 5
Glutamate receptor ionotropic, NMDA 1 and Glutamate receptor i... 4 30
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 2 2
Serine/threonine-protein kinase B-raf inhibitor AGN-PC-00CFYH ... 2 1
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 3 10
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 33 5
5-hydroxytryptamine receptor 4 and 5-hydroxytryptamine recepto... 5 14
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 10 0
Inosine-5'-monophosphate dehydrogenase inhibitor 5-[(1R)-1-[1-... 2 9
Glutamate receptor ionotropic, NMDA 1 ligand SureCN8971235 family 1 0
Gamma-aminobutyric acid receptor subunit pi and GABA theta sub... 1 1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B and cGMP-inhib... 2 4
Adenosine receptor A1 ligand 4-amino-2-phenyl-3H-pyrazolo[3,4-... 1 0
Serine/threonine-protein kinase Chk1 inhibitor 3-[(8-chloro-3-... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00309700 CHEMBL315183 Bioactive CHEMBL315183
CFAMM00309693 CHEMBL44581 Bioactive 8-chloro-2-(4-chlorophenyl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00309685 CHEMBL297867 Bioactive 2-(3-chlorophenyl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00309699 CHEMBL88126 Bioactive CHEMBL88126
CFAMM00309702 CHEMBL297056 Bioactive 8-chloro-2-(2-chlorophenyl)-1H-pyrazolo[4,3-c]quinolin-3-one
CFAMM00309680 CHEMBL315396 Bioactive CHEMBL315396
CFAMM00309694 CHEMBL116842 Bioactive Cgs-17867A

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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