CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2700
Family Name P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-5-amino-2-chlorobenzamide family
No. of Seeds 3 No. of Other Members 4
Family Centroid CFAMM00336916 Functional Category Bioactive
Superfamily P2X purinoceptor 7 and Cannabinoid receptor 2 Binder Superfamily
Class Class 3154

Cousin Family NamesSeedsMembers
Motilin receptor Ligand GSK962040 Family 30 457
Vasopressin V2 receptor Ligand FR161282 Family 17 83
Bifunctional epoxide hydrolase 2 Inhibitor N-(3-chloro-phenyl)... 2 43
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Coagulation factor X inhibitor 3-amino-4-chloro-N-[(1R)-2-[4-(... 1 1
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2,5-dichlor... 3 4
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2-amino-6-c... 1 0
D(3) dopamine receptor and Alpha-1B adrenergic receptor ligand... 11 8
Prelamin-A/C and Lysine-specific demethylase 4E inhibitor 4-(4... 2 3
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[(E... 24 11
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 8 1
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 5 2
D(3) dopamine receptor and D(2) dopamine receptor ligand RGH-1... 8 0
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor N-(2-... 1 0
P2X purinoceptor 7 inhibitor SureCN3652462 family 5 2
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
P2X purinoceptor 7 inhibitor N-(1-adamantylmethyl)-2-chloro-5-... 3 1
C-C chemokine receptor type 1 ligand N-[(2R)-1-[4-(4-chlorophe... 2 3
C-C chemokine receptor type 1 ligand 3-[2-(carbamoylamino)phen... 2 1
Melanin-concentrating hormone receptor 1 ligand SureCN5517533 ... 2 3
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 3 2
D(3) dopamine receptor and D(2) dopamine receptor ligand N-[4-... 4 0
Sodium-dependent noradrenaline transporter inhibitor AGN-PC-07... 1 1
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0
5-hydroxytryptamine receptor 2C and 5-hydroxytryptamine recept... 3 0
C-C chemokine receptor type 5 ligand AC1MHPA7 family 2 2
C-C chemokine receptor type 5 ligand AC1MHP8Y family 1 0
Prostaglandin G/H synthase 2 and Prostaglandin G/H synthase 1 ... 1 3
Melanin-concentrating hormone receptor 1 ligand 2-[1-(1-cyclop... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00336914 CHEMBL392378 Bioactive AGN-PC-01UJW0
CFAMM00336912 CHEMBL134194 Bioactive N-(1-adamantylmethyl)-3-amino-2-chlorobenzamide
CFAMM00336916 CHEMBL129982 Bioactive N-(1-adamantylmethyl)-5-amino-2-chlorobenzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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