CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27007
Family Name Acetylcholinesterase inhibitor CHEMBL267591 family
No. of Seeds 5 No. of Other Members 0
Family Centroid CFAMM00480999 Functional Category Bioactive
Superfamily Acetylcholinesterase and Bifunctional epoxide hydrolase 2 Binder Superfamily
Class Class 840

Cousin Family NamesSeedsMembers
Transient receptor potential cation channel subfamily V member... 15 158
Gamma-aminobutyric acid receptor Ligand E-2007 Family 7 118
D(3) dopamine receptor Ligand SB-277011 Family 13 178
Substance-P receptor Ligand TAK-637 Family 18 63
Amg 423 family 7 47
C-C chemokine receptor type 3 Ligand YM-344031 Family 19 106
cGMP-dependent 3',5'-cyclic phosphodiesterase Inhibitor CP-461... 4 34
cGMP-inhibited 3',5'-cyclic phosphodiesterase A and Cytochrome... 9 40
Alpha-1A adrenergic receptor Ligand L-771688 Family 8 14
Transient receptor potential cation channel subfamily V member... 6 23
D(4) dopamine receptor Ligand ABT-670 Family 4 14
Vasopressin V1a receptor and Vasopressin V1b receptor Ligand D... 10 19
Dipeptidyl peptidase 4 inhibitor (1S,3S,5S)-2-[(2S)-2-amino-2-... 3 5
Neuropeptide Y receptor type 5 ligand 2-[4-(benzenesulfonamido... 2 27
Substance-K receptor ligand N-[1-[[(2R)-5-[4-(oxan-4-ylmethyl)... 2 0
Renin and Potassium voltage-gated channel subfamily H member 2... 9 2
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 20 2
Probable G-protein coupled receptor 142 ligand (2S)-N-(2-oxo-5... 2 1
Renin inhibitor (E)-but-2-enedioic acid;(3S,5R)-5-[4-(2-chloro... 6 8


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00481001 CHEMBL413242 Bioactive CHEMBL413242
CFAMM00481000 CHEMBL244230 Bioactive CHEMBL244230
CFAMM00480999 CHEMBL267591 Bioactive CHEMBL267591
CFAMM00481003 CHEMBL389374 Bioactive CHEMBL389374
CFAMM00481002 CHEMBL413241 Bioactive CHEMBL413241

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

39240 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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