CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27014
Family Name Mu-type opioid receptor ligand 2-[[2-[(2R)-2-ethyl-4-(4-fluorophenyl)-2-methyloxan-4-yl]ethylamino]methyl]phenol family
No. of Seeds 1 No. of Other Members 3
Family Centroid CFAMM00481044 Functional Category Bioactive with Natural Product
Superfamily Cathepsin D and Beta-secretase 1 Binder Superfamily 9
Class Class 4595

Cousin Family NamesSeedsMembers
Serotonin re-uptake Inhibitor Fluoxetine Family 18 682
Noradrenergic re-uptake Inhibitor Reboxetine Family 26 206
Substance-P receptor Ligand Ezlopitant Family 10 207
Potassium voltage-gated channel subfamily H member 2 and Sodiu... 33 83
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 25 50
Adenosine receptor A3 and Muscarinic acetylcholine receptor M2... 4 31
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 41
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 5 11
Sodium-dependent dopamine transporter and Sodium-dependent nor... 6 13
Prelamin-A/C inhibitor CHEMBL1495780 family 1 4
Transporter and Sodium-dependent serotonin transporter inhibit... 1 5
Substance-P receptor ligand (5S,10S)-5-(4-fluorophenyl)-10-(2-... 3 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00481044 CHEMBL2443282 Bioactive 2-[[2-[(2R)-2-ethyl-4-(4-fluorophenyl)-2-methyloxan-4-yl]ethylamino]methyl]phenol

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27285 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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