CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27070
Family Name Sodium- and chloride-dependent glycine transporter 1 inhibitor 2-[2-[2-(2-chlorophenyl)-4-(4-methoxy-3-methylphenyl)phenoxy]ethyl-methylamino]acetic acid family
No. of Seeds 5 No. of Other Members 3
Family Centroid CFAMM00481282 Functional Category Bioactive
Superfamily Sodium- and Prostaglandin E2 receptor EP3 subtype Binder Superfamily
Class Class 4633

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand triphenyl ethylene stilbene derivati... 22 420
Sodium- and chloride-dependent glycine transporter 1 Inhibitor... 6 33
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 1 0
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 2 1


External ID

Functional Category

Molecule Name

CFAMM00481286 CHEMBL399033 Bioactive 2-[2-[2-(2-chlorophenyl)-4-(2,3-dihydro-1,4-benzodioxin-6-yl)phenoxy]ethyl-methylamino]acetic acid
CFAMM00481279 CHEMBL248734 Bioactive SureCN6279217
CFAMM00481283 CHEMBL404856 Bioactive SureCN8272806
CFAMM00481282 CHEMBL251775 Bioactive 2-[2-[2-(2-chlorophenyl)-4-(4-methoxy-3-methylphenyl)phenoxy]ethyl-methylamino]acetic acid
CFAMM00481281 CHEMBL399784 Bioactive 2-[2-[2-(2-chlorophenyl)-4-(2,3-dihydro-1-benzofuran-5-yl)phenoxy]ethyl-methylamino]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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