CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27071
Family Name C-X-C chemokine receptor type 3 ligand 3-[3,5-bis(trifluoromethyl)phenyl]-1-[1-[[(1S,5R)-6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methyl]piperidin-4-yl]imidazolidine-2,4-dione family
No. of Seeds 3 No. of Other Members 5
Family Centroid CFAMM00481291 Functional Category Bioactive
Superfamily C-X-C chemokine receptor type 3 Binder Superfamily 3
Class Class 220

Cousin Family NamesSeedsMembers
Mu-type opioid receptor Ligand Fentanyl Family 9 647
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 13
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
Bifunctional epoxide hydrolase 2 Inhibitor 1-phenyl-3-(1-propi... 22 183
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,3,4-trifluorop... 2 2
D(4) dopamine receptor ligand 1-Piperidineacetamide, 4-(2-cyan... 3 7
C-X-C chemokine receptor type 3 and Muscarinic acetylcholine r... 1 0


External ID

Functional Category

Molecule Name

CFAMM00481293 CHEMBL249178 Bioactive 1-[1-[[(1S,5R)-6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methyl]piperidin-4-yl]-3-[3-fluoro-5-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
CFAMM00481291 CHEMBL248773 Bioactive 3-[3,5-bis(trifluoromethyl)phenyl]-1-[1-[[(1S,5R)-6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methyl]piperidin-4-yl]imidazolidine-2,4-dione
CFAMM00481290 CHEMBL439399 Bioactive 1-[3,5-bis(trifluoromethyl)phenyl]-3-[1-[[(1S,5R)-6,6-dimethyl-4-bicyclo[3.1.1]hept-3-enyl]methyl]piperidin-4-yl]urea

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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