CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27079
Family Name Sodium- and chloride-dependent glycine transporter 1 inhibitor 2-[methyl-[2-[4-(3-methylphenyl)-2-(thiophene-2-carbonyl)phenoxy]ethyl]amino]acetic acid family
No. of Seeds 8 No. of Other Members 5
Family Centroid CFAMM00481312 Functional Category Bioactive
Superfamily DNA-dependent protein kinase catalytic subunit Inhibitor 2-morpholin-4-yl-8-phenoxathiin-4-ylchromen-4-one Superfamily
Class Class 2267

Cousin Family NamesSeedsMembers
Oestrogen receptor Ligand Raloxifene Family 4 169
DNA-dependent protein kinase catalytic subunit Inhibitor 2-mor... 2 46
DNA-dependent protein kinase catalytic subunit Inhibitor 2-mor... 3 0
Leukotriene A-4 hydrolase inhibitor SureCN2108222 family 3 9
Retinoic acid receptor gamma and Retinoic acid receptor alpha ... 1 5
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 3 0
Sodium- and chloride-dependent glycine transporter 1 inhibitor... 2 1


External ID

Functional Category

Molecule Name

CFAMM00481311 CHEMBL249760 Bioactive 2-[2-[4-(3-chlorophenyl)-2-(thiophene-2-carbonyl)phenoxy]ethyl-methylamino]acetic acid
CFAMM00481319 CHEMBL400396 Bioactive AGN-PC-04UNK1
CFAMM00481316 CHEMBL249970 Bioactive 2-[2-[4-(3,4-dimethylphenyl)-2-(thiophene-2-carbonyl)phenoxy]ethyl-methylamino]acetic acid
CFAMM00481315 CHEMBL399961 Bioactive 2-[2-[4-(4-methoxy-3-methylphenyl)-2-(thiophene-2-carbonyl)phenoxy]ethyl-methylamino]acetic acid
CFAMM00481314 CHEMBL249968 Bioactive 2-[methyl-[2-[4-(4-methylphenyl)-2-(thiophene-2-carbonyl)phenoxy]ethyl]amino]acetic acid
CFAMM00481322 CHEMBL399959 Bioactive SureCN8272137
CFAMM00481313 CHEMBL249969 Bioactive 2-[2-[4-(4-methoxyphenyl)-2-(thiophene-2-carbonyl)phenoxy]ethyl-methylamino]acetic acid
CFAMM00481312 CHEMBL249762 Bioactive 2-[methyl-[2-[4-(3-methylphenyl)-2-(thiophene-2-carbonyl)phenoxy]ethyl]amino]acetic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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