CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27100
Family Name Interstitial collagenase and Matrix metalloproteinase-9 inhibitor N-tert-butyl-2-[(2S,5R)-2-[(4-nitrophenyl)methyl]-3,6-dioxo-5-(sulfanylmethyl)piperazin-1-yl]-3-phenylpropanamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00481381 Functional Category Bioactive
Superfamily Delta-type opioid receptor and Kappa-type opioid receptor Ligand Dcp-c[d-cys-gly-phe(pno2)-d-cys]nh2 Superfamily
Class Class 1625

Cousin Family NamesSeedsMembers
Nitric oxide synthase, brain Inhibitor NXN-188 Family 1 7
Motilin receptor Ligand GSK962040 Family 30 457
Vasopressin-neurophysin 2-copeptin Inhibitor Niravoline Family 7 45
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Inhibitor 1-methyl-5-(... 6 17
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 2 7
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
D(4) dopamine receptor ligand AGN-PC-074VC9 family 2 3
Lethal factor inhibitor (2R)-2-(4-fluoro-3,5-dimethylanilino)-... 11 8
Sigma non-opioid intracellular receptor 1 ligand 2-(2-nitrophe... 2 5
Baculoviral IAP repeat-containing protein 2 and E3 ubiquitin-p... 2 1
Dipeptidyl peptidase 4 inhibitor [(2S,4S)-4-(5-nitro-2,3-dihyd... 2 6
Mu-type opioid receptor ligand CHEMBL2310836 family 4 4
Kappa-type opioid receptor ligand 1-[4-acetyl-2-[[(3S)-3-hydro... 1 0
Neutrophil elastase inhibitor 1-[(2S)-3-methyl-2-[(4-nitrobenz... 1 1
Kappa-type opioid receptor ligand N-[(2S)-1-(2,5-dihydropyrrol... 1 1
Peptide deformylase, mitochondrial inhibitor (2S)-N-[(2S)-6-am... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00481382 CHEMBL284422 Bioactive N-tert-butyl-2-[(2S,5R)-2-[(4-nitrophenyl)methyl]-3,6-dioxo-5-(sulfanylmethyl)piperazin-1-yl]nonanamide
CFAMM00481381 CHEMBL251687 Bioactive N-tert-butyl-2-[(2S,5R)-2-[(4-nitrophenyl)methyl]-3,6-dioxo-5-(sulfanylmethyl)piperazin-1-yl]-3-phenylpropanamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27511 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543