CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27112
Family Name Disintegrin and metalloproteinase domain-containing protein 10 and 72 kDa type IV collagenase inhibitor benzyl (6S,7S)-7-(hydroxycarbamoyl)-6-(4-phenyl-3,4-dihydro-2H-pyridine-1-carbonyl)-5-azaspiro[2.5]octane-5-carboxylate family
No. of Seeds 1 No. of Other Members 0
Family Centroid CFAMM00481410 Functional Category Bioactive
Superfamily Disintegrin and Neutrophil collagenase Binder Superfamily
Class Class 1181

Cousin Family NamesSeedsMembers
Flovagatran family 12 546
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Neuromedin-K receptor Ligand PD-160946 Family 10 32
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Genome polyprotein Inhibitor Acasp-glu-cha-val-prb-cys Family 13 18
72 kDa type IV collagenase and Disintegrin and metalloproteina... 1 13
Receptor tyrosine-protein kinase erbB-2 and Disintegrin and me... 3 4


External ID

Functional Category

Molecule Name

CFAMM00481410 CHEMBL252678 Bioactive benzyl (6S,7S)-7-(hydroxycarbamoyl)-6-(4-phenyl-3,4-dihydro-2H-pyridine-1-carbonyl)-5-azaspiro[2.5]octane-5-carboxylate

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

Last update by



108138 visits since 2014 .........


Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

All rights reserved.

Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links


Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543