CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27141
Family Name Calcitonin gene-related peptide type 1 receptor ligand N-[5-(4-hydroxyphenyl)-1-methyl-2-oxopyridin-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide family
No. of Seeds 3 No. of Other Members 1
Family Centroid CFAMM00481527 Functional Category Bioactive
Superfamily Alpha-1B adrenergic receptor and 5-hydroxytryptamine receptor 1A Binder Superfamily 3
Class Class 1382

Cousin Family NamesSeedsMembers
Reverse transcriptase Inhibitor Nevirapine Family 23 640
Calcitonin gene-related peptide type 1 receptor Ligand Telcage... 25 124
Cyclin-dependent kinase 4 Inhibitor PD-332991 Family 13 155
Translocator protein Inhibitor Emapunil Family 7 89
Class II cytokine receptor Ligand IL-10 Family 7 45
Tyrosine kinase Inhibitor PKI166 Family 17 198
Beta-secretase 1 Inhibitor N~3~-(3-pyridin-3-ylbenzyl)pyridine... 31 66
Serine/threonine-protein kinase B-raf Inhibitor 2-(benzylamino... 7 117
Glycogen synthase kinase-3 beta and Mitogen-activated protein ... 8 8
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 13 15
Liver carboxylesterase 1 Inhibitor SM-32504 Family 3 28
Histamine H3 receptor ligand 1-[1-[1-[(2-aminopyridin-4-yl)met... 16 9
G1/S-specific cyclin-D1 and G1/S-specific cyclin-D3 inhibitor ... 6 3
cGMP-specific 3',5'-cyclic phosphodiesterase and Rod cGMP-spec... 42 3
cGMP-specific 3',5'-cyclic phosphodiesterase and Rod cGMP-spec... 24 5
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor 8-(2-hy... 24 0
Melanin-concentrating hormone receptor 1 ligand 1-[6-[(3R)-3-a... 1 5
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subun... 4 0
Cannabinoid receptor 2 and Cannabinoid receptor 1 ligand AGN-P... 7 2
cGMP-specific 3',5'-cyclic phosphodiesterase inhibitor AGN-PC-... 7 6
Serine/threonine-protein kinase mTOR inhibitor 3-(cyclohexylme... 2 1
Calcitonin gene-related peptide type 1 receptor ligand N-(1-me... 1 3
Calcitonin gene-related peptide type 1 receptor ligand N-[1-me... 1 1


External ID

Functional Category

Molecule Name

CFAMM00481530 CHEMBL270796 Bioactive N-[5-(4-hydroxyphenyl)-1-(2-methoxyethyl)-2-oxopyridin-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
CFAMM00481529 CHEMBL255136 Bioactive N-[5-(4-hydroxyphenyl)-2-oxo-1-(2,2,2-trifluoroethyl)pyridin-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide
CFAMM00481527 CHEMBL270390 Bioactive N-[5-(4-hydroxyphenyl)-1-methyl-2-oxopyridin-3-yl]-4-(2-oxo-3H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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