CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27159
Family Name 5-hydroxytryptamine receptor 2A and D(2) dopamine receptor ligand 1-(4-chlorophenyl)-4-[[2-(2-fluoroethoxy)-4,5-dimethoxyphenyl]methyl]piperazine family
No. of Seeds 2 No. of Other Members 6
Family Centroid CFAMM00481622 Functional Category Bioactive with Natural Product
Superfamily Beta-lactamase and D(2) dopamine receptor Binder Superfamily 4
Class Class 2479

Cousin Family NamesSeedsMembers
Alpha-1A adrenergic receptor Ligand Naftopidil Family 15 119
5-hydroxytryptamine receptor 1A and Sodium-dependent dopamine ... 8 41
Galanin receptor type 1 and Galanin receptor type 2 Ligand Gal... 55 132
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 9 28
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 21 13
Acetylcholinesterase Inhibitor 6-methyl-4-(4-phenylpiperazin-1... 6 622
Alpha-1A adrenergic receptor and Alpha-1D adrenergic receptor ... 3 2
Neuropeptide S receptor and Prelamin-A/C ligand CHEMBL1352632 ... 1 25
Alpha-1B adrenergic receptor and Alpha-1D adrenergic receptor ... 2 9
Translocator protein inhibitor [11C]DAA1106 family 15 2
D(3) dopamine receptor and D(2) dopamine receptor ligand (5R)-... 2 0
5-hydroxytryptamine receptor 1A ligand AGN-PC-0034EG family 5 2
5-hydroxytryptamine receptor 1A and Sodium-dependent serotonin... 1 1
NP 3-(2-(3,4-dihydroquinolin-1(2h)-yl)-2-oxoethyl)-7,8-dihydro... 2 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00481622 CHEMBL256637 Bioactive 1-(4-chlorophenyl)-4-[[2-(2-fluoroethoxy)-4,5-dimethoxyphenyl]methyl]piperazine
CFAMM00481626 CHEMBL270406 Bioactive 1-[[2-(2-fluoroethoxy)-4,5-dimethoxyphenyl]methyl]-4-(2-methoxyphenyl)piperazine

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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