CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27163
Family Name Insulin-like growth factor 1 receptor ligand (3E)-4-[2-(4-bromopyrazol-1-yl)ethylamino]-3-(4-methyl-6-morpholin-4-yl-1,3-dihydrobenzimidazol-2-ylidene)pyridin-2-one family
No. of Seeds 5 No. of Other Members 13
Family Centroid CFAMM00481663 Functional Category Bioactive
Superfamily cAMP and Tyrosine-protein kinase SYK Binder Superfamily
Class Class 3568

Cousin Family NamesSeedsMembers
Telomerase reverse transcriptase Inhibitor HOE-33258 Family 10 33
5-hydroxytryptamine receptor 1D and 5-hydroxytryptamine recept... 14 13
Adenosine deaminase inhibitor 1o5r family 2 6
Tyrosine-protein kinase JAK1 inhibitor CHEMBL2206623 family 10 11
Cytochrome P450 3A4 and Insulin-like growth factor 1 receptor ... 24 57
Platelet-derived growth factor receptor beta and Vascular endo... 5 12
Serine/threonine-protein kinase Chk1 inhibitor SureCN5547496 f... 2 1
Aurora kinase B and Aurora kinase A inhibitor 1-cyclohexyl-3-[... 4 0
Platelet-derived growth factor receptor beta and Fibroblast gr... 10 0
Aurora kinase A and Aurora kinase B inhibitor N-[(3E)-3-[5-(mo... 3 2
Insulin-like growth factor 1 receptor and Cytochrome P450 3A4 ... 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00481648 CHEMBL256909 Bioactive methyl 1-[2-[[(3E)-3-(4-methyl-6-morpholin-4-yl-1,3-dihydrobenzimidazol-2-ylidene)-2-oxopyridin-4-yl]amino]ethyl]pyrazole-4-carboxylate
CFAMM00481662 CHEMBL257115 Bioactive (3E)-4-[2-[4-bromo-3-(hydroxymethyl)pyrazol-1-yl]ethylamino]-3-(4-methyl-6-morpholin-4-yl-1,3-dihydrobenzimidazol-2-ylidene)pyridin-2-one
CFAMM00481654 CHEMBL257326 Bioactive (3E)-4-[2-(4-chloro-3-methylpyrazol-1-yl)ethylamino]-3-(4-methyl-6-morpholin-4-yl-1,3-dihydrobenzimidazol-2-ylidene)pyridin-2-one
CFAMM00481649 CHEMBL256908 Bioactive ethyl 1-[2-[[(3E)-3-(4-methyl-6-morpholin-4-yl-1,3-dihydrobenzimidazol-2-ylidene)-2-oxopyridin-4-yl]amino]ethyl]pyrazole-4-carboxylate
CFAMM00481663 CHEMBL257114 Bioactive (3E)-4-[2-(4-bromopyrazol-1-yl)ethylamino]-3-(4-methyl-6-morpholin-4-yl-1,3-dihydrobenzimidazol-2-ylidene)pyridin-2-one

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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