CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27172
Family Name Histone deacetylase 1 inhibitor N-(2-aminophenyl)-4-[[[4-(cyclopropylamino)-6-(2,3-dihydro-1H-inden-2-ylamino)-1,3,5-triazin-2-yl]amino]methyl]benzamide family
No. of Seeds 5 No. of Other Members 3
Family Centroid CFAMM00481684 Functional Category Bioactive
Superfamily ALK tyrosine kinase receptor and Histone deacetylase 1 Binder Superfamily
Class Class 950

Cousin Family NamesSeedsMembers
Mast/stem cell growth factor receptor Kit and Abelson tyrosine... 6 537
JAK Inhibitor Momelotinib Family 33 83
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 19 103
Adenosine receptor A1 Ligand N-(4,6-diphenylpyrimidin-2-yl)ben... 4 8
Bifunctional dihydrofolate reductase-thymidylate synthase and ... 6 11
Mitogen-activated protein kinase 14 inhibitor AGN-PC-04UPTJ fa... 3 20
ALK tyrosine kinase receptor ligand 4-fluoro-N-[6-(piperidin-1... 10 7
Melanocortin receptor 4 ligand AGN-PC-076AMO family 17 8
G-protein coupled bile acid receptor 1 ligand 2-(ethylamino)-6... 5 4
Dihydrofolate reductase and Bifunctional dihydrofolate reducta... 3 2
Tyrosine-protein kinase ITK/TSK inhibitor AGN-PC-077RDJ family 15 1
Tyrosine-protein kinase ITK/TSK and Insulin receptor ligand AG... 5 1
Histone deacetylase 3 and Nuclear receptor corepressor 1 ligan... 7 4
Histone deacetylase 1 inhibitor N-(2-aminophenyl)-4-[[(4,6-dim... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00481684 CHEMBL257631 Bioactive N-(2-aminophenyl)-4-[[[4-(cyclopropylamino)-6-(2,3-dihydro-1H-inden-2-ylamino)-1,3,5-triazin-2-yl]amino]methyl]benzamide
CFAMM00481690 CHEMBL258297 Bioactive N-(2-aminophenyl)-4-[[[4-(2,3-dihydro-1H-inden-2-ylamino)-6-morpholin-4-yl-1,3,5-triazin-2-yl]amino]methyl]benzamide
CFAMM00481683 CHEMBL401751 Bioactive N-(2-aminophenyl)-4-[[[4-(2,3-dihydro-1H-inden-2-ylamino)-6-(2-morpholin-4-ylethylamino)-1,3,5-triazin-2-yl]amino]methyl]benzamide
CFAMM00481687 CHEMBL257835 Bioactive 4-[[[4-amino-6-(1,3-dihydroisoindol-2-yl)-1,3,5-triazin-2-yl]amino]methyl]-N-(2-aminophenyl)benzamide
CFAMM00481686 CHEMBL403285 Bioactive N-(2-aminophenyl)-4-[[[4-amino-6-(2-phenylethylamino)-1,3,5-triazin-2-yl]amino]methyl]benzamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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