CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27183
Family Name Adenosine receptor A2a and Adenosine receptor A1 ligand thiophen-3-yl-[2-(trifluoromethyl)thieno[3,2-d]pyrimidin-4-yl]methanone family
No. of Seeds 2 No. of Other Members 1
Family Centroid CFAMM00481711 Functional Category Bioactive
Superfamily Adenosine receptor A2a and Adenosine receptor A1 Binder Superfamily 2
Class Class 3133

Cousin Family NamesSeedsMembers
Omega 1 Benzodiazepine receptor Ligand Indiplon Family 4 25
Adenosine receptor A2b and Adenosine receptor A2a ligand SureC... 1 26
NAD-dependent protein deacetylase sirtuin-2 and NAD-dependent ... 8 12
Epidermal growth factor receptor and Vascular endothelial grow... 7 0
Adenosine receptor A2a and Adenosine receptor A1 ligand [2-(2-... 2 9


External ID

Functional Category

Molecule Name

CFAMM00481711 CHEMBL258589 Bioactive thiophen-3-yl-[2-(trifluoromethyl)thieno[3,2-d]pyrimidin-4-yl]methanone
CFAMM00481710 CHEMBL405028 Bioactive phenyl-[2-(trifluoromethyl)thieno[3,2-d]pyrimidin-4-yl]methanone

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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