CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27205
Family Name Geranylgeranyl pyrophosphate synthase inhibitor [1-Hydroxy-2-(1,1':3',1''-Terphenyl-3-Yloxy)Ethane-1,1-Diyl]Bis(Phosphonic Acid) family
No. of Seeds 1 No. of Other Members 2
Family Centroid CFAMM00481794 Functional Category Bioactive
Superfamily Thyroid hormone receptor beta Ligand MB-07811 Superfamily
Class Class 470

Cousin Family NamesSeedsMembers
Cyclooxygenase Inhibitor Fenoprofen Family 4 1077
Oestrogen receptor Ligand Chlorotrianisene Family 2 102
Translocator protein Inhibitor Dextofisopam Family 3 250
Thyroid hormone receptor beta Ligand MB-07811 Family 1 2
Cytosolic phospholipase A2 Inhibitor 1,1,1-trifluoro-6-(4-hexy... 9 86
Abelson tyrosine-protein kinase 2 Inhibitor 3'',5''-dimethoxy-... 3 9
5-hydroxytryptamine receptor 1A and D(2) dopamine receptor Lig... 2 214
NAD(P)H dehydrogenase [quinone] 1 Inhibitor NSC-106547 Family 3 65
Oxysterols receptor LXR-alpha and Oxysterols receptor LXR-beta... 4 37
Squalene synthase Inhibitor BMS-187745 Family 7 26
Thyroid hormone receptor alpha and Thyroid hormone receptor be... 5 8
Geranylgeranyl pyrophosphate synthase inhibitor bisphosphonate... 1 1


External ID

Functional Category

Molecule Name

CFAMM00481794 CHEMBL260880 Bioactive [1-Hydroxy-2-(1,1':3',1''-Terphenyl-3-Yloxy)Ethane-1,1-Diyl]Bis(Phosphonic Acid)

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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