CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27217
Family Name Lanosterol synthase and Squalene--hopene cyclase inhibitor AGN-PC-074E1A family
No. of Seeds 2 No. of Other Members 5
Family Centroid CFAMM00481851 Functional Category Bioactive with Natural Product
Superfamily Lanosterol synthase and Squalene--hopene cyclase inhibitor AGN-PC-074E1A Superfamily
Class Class 2656

Cousin Family NamesSeedsMembers
Noradrenergic re-uptake and Serotonin re-uptake Inhibitor Diet... 29 276
DNA Binder Procarbazine Family 8 358
Bavisant family 9 65
Hemagglutinin Inhibitor Cl 385319 Family 18 101
Enoyl-[acyl-carrier-protein] reductase [NADH] Inhibitor N-(4-m... 8 37
Histone deacetylase 1 and Histone deacetylase 2 Inhibitor N-(6... 1 12
Cathepsin K and Cathepsin L1 Inhibitor N-benzoyl-phenylalanyl-... 13 77
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 41 24
Arachidonate 5-lipoxygenase Inhibitor N-hydroxy-n-methyl-benza... 3 9
Muscarinic acetylcholine receptor M1 and Muscarinic acetylchol... 2 80
Voltage-dependent calcium channel gamma-1 subunit Ligand NP-11... 8 9
Sigma non-opioid intracellular receptor 1 and 5-hydroxytryptam... 2 7


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00481846 CHEMBL66359 Bioactive AGN-PC-074DUR
CFAMM00481851 CHEMBL262532 Bioactive AGN-PC-074E1A

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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