CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27219
Family Name Thromboxane-A synthase inhibitor SureCN9825871 family
No. of Seeds 6 No. of Other Members 3
Family Centroid CFAMM00481863 Functional Category Bioactive
Superfamily Huntingtin and Thyrotropin receptor Binder Superfamily 3
Class Class 4864

Cousin Family NamesSeedsMembers
Thromboxane A2 receptor Ligand Ridogrel Family 7 83
Histamine H1 receptor Ligand (s)-(+)-dimethindene Maleate Family 6 12
Macrophage metalloelastase Inhibitor PF-00356231 Family 5 79
Thromboxane-A synthase Inhibitor CGS-22652 Family 37 95
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 17 14
Thromboxane-A synthase and Thromboxane A2 receptor ligand (E)-... 2 1
Protein farnesyltransferase/geranylgeranyltransferase type-1 s... 6 4
Mitogen-activated protein kinase kinase kinase 8 inhibitor AGN... 2 2


External ID

Functional Category

Molecule Name

CFAMM00481863 CHEMBL419900 Bioactive SureCN9825871
CFAMM00481855 CHEMBL330592 Bioactive SureCN9825437
CFAMM00481861 CHEMBL98477 Bioactive SureCN9825241
CFAMM00481860 CHEMBL263019 Bioactive SureCN9826605
CFAMM00481857 CHEMBL98444 Bioactive SureCN9826585
CFAMM00481856 CHEMBL97891 Bioactive (Z)-2,2-dimethyl-8-pyridin-3-yl-8-thiophen-2-yloct-7-enoic acid

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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