CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2725
Family Name Acetylcholinesterase inhibitor [3-(4-chlorophenyl)-5-hexylsulfanyl-1,2,4-triazol-1-yl]-piperidin-1-ylmethanone family
No. of Seeds 11 No. of Other Members 16
Family Centroid CFAMM00337211 Functional Category Bioactive
Superfamily Cholinesterase and Pyruvate kinase PKM Binder Superfamily
Class Class 3619

Cousin Family NamesSeedsMembers
Hormone-sensitive lipase and Cholinesterase inhibitor N,N-dime... 3 3
Prelamin-A/C and Nuclear receptor ROR-gamma ligand CHEMBL13680... 1 7
Fatty-acid amide hydrolase 1 inhibitor 4-(3-phenyl-1,2,4-thiad... 2 1
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor 3,5-b... 4 6
Corticosteroid 11-beta-dehydrogenase isozyme 1 inhibitor AGN-P... 17 0
Adenosine receptor A1 and Adenosine receptor A3 ligand F3394-1... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00337241 CHEMBL133580 Bioactive AGN-PC-005OW6
CFAMM00337248 CHEMBL130628 Bioactive [3-(4-chlorophenyl)-5-(2,2,2-trifluoroethylsulfanyl)-1,2,4-triazol-1-yl]-piperidin-1-ylmethanone
CFAMM00337211 CHEMBL335158 Bioactive [3-(4-chlorophenyl)-5-hexylsulfanyl-1,2,4-triazol-1-yl]-piperidin-1-ylmethanone
CFAMM00337229 CHEMBL336398 Bioactive AGN-PC-005NTN
CFAMM00337227 CHEMBL131588 Bioactive 3-(4-chlorophenyl)-N-methyl-N-phenyl-5-(2,2,2-trifluoroethylsulfanyl)-1,2,4-triazole-1-carboxamide
CFAMM00337245 CHEMBL335112 Bioactive AGN-PC-00A2LJ
CFAMM00337218 CHEMBL130098 Bioactive ZINC00115374
CFAMM00337233 CHEMBL334395 Bioactive 3-(4-chlorophenyl)-N,N-dimethyl-5-propylsulfanyl-1,2,4-triazole-1-carboxamide
CFAMM00337225 CHEMBL336524 Bioactive AGN-PC-005UWH
CFAMM00337242 CHEMBL130666 Bioactive AGN-PC-007IZJ
CFAMM00337232 CHEMBL131536 Bioactive AGN-PC-004FS7

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48688 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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