CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM2728
Family Name Cathepsin B and Calpain-1 catalytic subunit inhibitor AGN-PC-075LAR family
No. of Seeds 2 No. of Other Members 0
Family Centroid CFAMM00337269 Functional Category Bioactive
Superfamily Protein kinase C eta type and Protein kinase C delta type Inhibitor 8-octyl-benzolactam-v9 Superfamily
Class Class 348

Cousin Family NamesSeedsMembers
Angiotensin-converting enzyme Inhibitor Benazepril Family 7 123
Integrin alpha-4 Inhibitor BIO-1211 Family 16 83
Cyclophilin receptor and Cyclosporine receptor Ligand D-43787 ... 2 13
Cathepsin F and Cruzipain Inhibitor Benzoyl-arginine-alanine-m... 49 348
Cathepsin B and Cathepsin L1 Inhibitor MDL-2170 Family 17 24
Cholecystokinin receptor type A Ligand VL-1499 Family 12 133
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 14 110
Genome polyprotein Inhibitor Acasp-glu-cha-val-prb-cys Family 13 18
Pol polyprotein inhibitor benzyl N-[(2S,3R)-1-[[(2S,3R,4R)-4-(... 5 26
Angiotensin-converting enzyme inhibitor (2R)-1-[4-carboxy-4-(p... 3 3
Caspase-1 inhibitor (3S)-5-[[(3aS,7aS)-2-oxo-3a,4,5,6,7,7a-hex... 3 0
Cathepsin L1 and Cathepsin K inhibitor benzyl N-[(2S)-4-methyl... 8 22
Caspase-9 and Caspase-8 inhibitor 4-fluoro-2-[[2-[[(2S)-3-meth... 1 11
Pol polyprotein inhibitor 2,5-bis[(2-{[(benzyloxy)carbonyl]ami... 2 3
Pol polyprotein inhibitor AC1NS2O6 family 3 0
Calpain-1 catalytic subunit inhibitor (4-nitrophenyl)methyl N-... 1 13
Integrin beta-3 and Integrin alpha-V inhibitor (2S)-2-[(4-meth... 2 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00337270 CHEMBL132732 Bioactive AGN-PC-075L3I
CFAMM00337269 CHEMBL130122 Bioactive AGN-PC-075LAR

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27523 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


All rights reserved.

   
 
 
Computer-aided Drug Design
about BIDD |  databases |  software |  teaching |  research |  links

 

Department of Computational Science | National University of Singapore | Blk S17, 3 Science Drive 2, Singapore 117543