CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27359
Family Name Reverse transcriptase/RNaseH inhibitor (4S)-5-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1,3-dihydroquinazolin-2-one family
No. of Seeds 5 No. of Other Members 7
Family Centroid CFAMM00482269 Functional Category Bioactive
Superfamily Reverse transcriptase/RNaseH Binder Superfamily 8
Class Class 1700

Cousin Family NamesSeedsMembers
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A ... 2 6
Inosine-5'-monophosphate dehydrogenase inhibitor 1-[4-chloro-3... 3 5
Inosine-5'-monophosphate dehydrogenase inhibitor 1-(3,4-dichlo... 1 1
Reverse transcriptase/RNaseH inhibitor (4S)-6-fluoro-4-(3-meth... 7 1
Reverse transcriptase/RNaseH inhibitor AC1L9SWL family 3 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00482275 CHEMBL29274 Bioactive Dpc 083
CFAMM00482265 CHEMBL64521 Bioactive (4S)-5-chloro-6-fluoro-4-(3-methylbut-1-ynyl)-4-(trifluoromethyl)-1,3-dihydroquinazolin-2-one
CFAMM00482271 CHEMBL59458 Bioactive (4S)-5-chloro-4-(2-cyclopropylethynyl)-6-fluoro-4-(trifluoromethyl)-1,3-dihydroquinazolin-2-one
CFAMM00482269 CHEMBL293037 Bioactive (4S)-5-chloro-4-(2-cyclopropylethynyl)-4-(trifluoromethyl)-1,3-dihydroquinazolin-2-one
CFAMM00482268 CHEMBL283619 Bioactive DPC 961

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

85066 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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