CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27387
Family Name Adenosine receptor A2b and Adenosine receptor A1 ligand N-[(3Z)-3-(2,6-dioxo-1,3-dipropylpurin-8-ylidene)-2-methyl-1H-pyrazol-5-yl]-2-[4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]acetamide family
No. of Seeds 2 No. of Other Members 2
Family Centroid CFAMM00482388 Functional Category Bioactive
Superfamily Adenosine receptor A1 and Adenosine receptor A2b Binder Superfamily 4
Class Class 3548

Cousin Family NamesSeedsMembers
Adenosine receptor A2b Ligand CVT-7124 Family 14 64
Tyrosine-protein kinase JAK2 inhibitor AGN-PC-09QJGR family 3 13
Serine/threonine-protein kinase RIO2 and Serine/threonine-prot... 12 13
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10... 1 1
Adenosine receptor A2a and Cytochrome P450 3A4 ligand N-[6-(3,... 5 2
Adenosine receptor A2b and Adenosine receptor A1 ligand N-(3,4... 1 8
Adenosine receptor A2b and Adenosine receptor A1 ligand 8-[1-[... 1 1


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00482388 CHEMBL286212 Bioactive N-[(3Z)-3-(2,6-dioxo-1,3-dipropylpurin-8-ylidene)-2-methyl-1H-pyrazol-5-yl]-2-[4-[[3-(trifluoromethyl)phenyl]methoxy]phenyl]acetamide
CFAMM00482385 CHEMBL32591 Bioactive 2-(1,3-benzodioxol-5-yl)-N-[(3Z)-3-(2,6-dioxo-1,3-dipropylpurin-8-ylidene)-2-methyl-1H-pyrazol-5-yl]acetamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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