CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27428
Family Name Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9352718 family
No. of Seeds 2 No. of Other Members 3
Family Centroid CFAMM00482625 Functional Category Bioactive
Superfamily Acyl-CoA:cholesterol acyltransferase and Sterol O-acyltransferase 1 Binder Superfamily 3
Class Class 4235

Cousin Family NamesSeedsMembers
Sodium channel Ligand iminostilbene derivative (tricyclic stru... 2 46
Androgen receptor Ligand YM-175735 Family 30 129
Cannabinoid receptor 1 Ligand 1-(bis(4-chlorophenyl)methyl)-3-... 4 44
Cannabinoid receptor 1 Ligand 1-[bis(4-iodophenyl)methyl]-3-(4... 4 13
Kinesin-like protein KIF11 Inhibitor N-(4'-bromo-3,3'-difluoro... 2 0
Kinesin-like protein KIF11 Inhibitor N-[4'-(trifluoromethyl)-4... 7 134
Delta-type opioid receptor and Kappa-type opioid receptor Liga... 7 13
5-hydroxytryptamine receptor 3A Ligand 1-(biphenyl-4-yl)-3-(4-... 20 67
5-hydroxytryptamine receptor 3B and 5-hydroxytryptamine recept... 4 24
DNA topoisomerase Inhibitor 6-(naphthalen-2-ylamino)-1h-pyrimi... 2 1
Histamine H3 receptor and Potassium voltage-gated channel subf... 1 0
Melanin-concentrating hormone receptor 1 ligand 1-[2-[4-(3-cya... 3 2
Bifunctional epoxide hydrolase 2 inhibitor 1-(2,3,4-trifluorop... 2 2
Carbonic anhydrase 1 and Carbonic anhydrase 2 inhibitor 1-(3,5... 2 0
Sterol O-acyltransferase 1 inhibitor SureCN7565101 family 2 10
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN13328411 ... 4 2
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 7 2
Acyl-CoA:cholesterol acyltransferase inhibitor SureCN9614694 f... 3 14
Acyl-CoA:cholesterol acyltransferase inhibitor 1-[2,6-di(propa... 2 0
Acyl-CoA:cholesterol acyltransferase inhibitor N-[[2,6-di(prop... 1 0
Sterol O-acyltransferase 1 inhibitor SureCN9848375 family 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00482625 CHEMBL290655 Bioactive SureCN9352718
CFAMM00482623 CHEMBL45377 Bioactive 1-[[1-(4-bromophenyl)cyclopentyl]methyl]-3-[2,6-di(propan-2-yl)phenyl]urea

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

27634 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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