CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27451
Family Name Aldose reductase inhibitor Spiro-cimqat family
No. of Seeds 6 No. of Other Members 8
Family Centroid CFAMM00482715 Functional Category Bioactive
Superfamily Aldose reductase and Calcitonin gene-related peptide type 1 receptor Binder Superfamily
Class Class 1613

Cousin Family NamesSeedsMembers
D(2) dopamine receptor ligand diphenylbutylpiperidine derivati... 43 161
Cannabinoid receptor 1 Ligand 1,3,5-triphenylimidazolidine-2,4... 2 17
Liver carboxylesterase 1 Inhibitor 7-chloro-1h-indole-2,3-dion... 6 5
Phospholipase D1 Inhibitor Halopemide Family 17 111
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 53 289
Bifunctional epoxide hydrolase 2 inhibitor AGN-PC-07ZBI0 family 2 16
5-hydroxytryptamine receptor 1A and Alpha-1B adrenergic recept... 5 14
E3 ubiquitin-protein ligase Mdm2 inhibitor (2'R,3R,3'S,5'S)-6-... 17 51
Gastrin/cholecystokinin type B receptor and Cholecystokinin re... 15 12
Melanocortin receptor 4 and Melanocortin receptor 5 ligand N-[... 16 117
Kappa-type opioid receptor and Mu-type opioid receptor ligand ... 3 6
Melanocortin receptor 4 ligand (3R)-N-[(2R)-3-(4-chlorophenyl)... 6 9
C-C chemokine receptor type 1 ligand SureCN3159355 family 7 9
Melanocortin receptor 4 ligand N-[(2R)-3-(4-chlorophenyl)-1-[4... 11 9
Growth hormone secretagogue receptor type 1 ligand N-[4,6-dich... 2 0
Melanocortin receptor 4 and Cytochrome P450 3A4 ligand 2-amino... 52 12
Melanocortin receptor 4 ligand N-[(1S)-1-[2-[4-[(3S,4R)-4-(4-c... 26 13
Nociceptin receptor and Delta-type opioid receptor ligand spir... 25 9
5-hydroxytryptamine receptor 7 ligand 7-chloro-3-[4-[4-(4-chlo... 2 0
Substance-K receptor and Neuromedin-K receptor ligand 1-benzyl... 3 10
Mu-type opioid receptor and Delta-type opioid receptor ligand ... 4 1
Integrin beta-2 and Intercellular adhesion molecule 1 inhibito... 1 5
5-hydroxytryptamine receptor 2A and 5-hydroxytryptamine recept... 2 0
Calcitonin gene-related peptide type 1 receptor and Dual speci... 4 0
Prelamin-A/C and Microtubule-associated protein tau inhibitor ... 1 0
C5a anaphylatoxin chemotactic receptor 1 ligand SureCN12047568... 1 1
Aldose reductase inhibitor (4R)-6-fluoro-3-methylspiro[1H-quin... 4 16
Aldose reductase inhibitor AGN-PC-00OGZL family 1 0
Aldose reductase inhibitor SureCN10775957 family 2 2


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00482709 CHEMBL416870 Bioactive SureCN10654196
CFAMM00482716 CHEMBL291854 Bioactive AGN-PC-000RZS
CFAMM00482715 CHEMBL292723 Bioactive Spiro-cimqat
CFAMM00482714 CHEMBL63974 Bioactive 6-chloro-3,7-dimethylspiro[1H-quinazoline-4,5'-imidazolidine]-2,2',4'-trione
CFAMM00482706 CHEMBL303362 Bioactive SureCN10654211
CFAMM00482713 CHEMBL65372 Bioactive 107583-21-1

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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