CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27476
Family Name Reverse transcriptase/RNaseH inhibitor 3Am-6Et-7,9-diMe-PBOA-5one family
No. of Seeds 4 No. of Other Members 1
Family Centroid CFAMM00482819 Functional Category Bioactive
Superfamily Reverse transcriptase/RNaseH and Prelamin-A/C Binder Superfamily
Class Class 2593

Cousin Family NamesSeedsMembers
Histamine H3 receptor Ligand GSK239512 Family 2 65
Delta-type opioid receptor and Mu-type opioid receptor Ligand ... 8 57
Bifunctional epoxide hydrolase 2 Inhibitor N-benzyl-6-(3,3,3-t... 21 62
Histamine H3 receptor ligand 6-[[2-[2-[(2R)-2-methylpyrrolidin... 2 0
Reverse transcriptase/RNaseH inhibitor 6Et-9Me-7NO2-PBOA-5one ... 2 5
Reverse transcriptase/RNaseH inhibitor 7CN-6Et-9Me-PBOA-5one f... 4 1
Reverse transcriptase/RNaseH inhibitor 2Cl-5MeSEt-PBOA-6one fa... 1 1


External ID

Functional Category

Molecule Name

CFAMM00482819 CHEMBL294171 Bioactive 3Am-6Et-7,9-diMe-PBOA-5one
CFAMM00482817 CHEMBL56501 Bioactive 3Am-8,9-diMe-6iPr-PBOA-5one
CFAMM00482816 CHEMBL56500 Bioactive 3Am-6,7,9triMe-PBOA-5one
CFAMM00482815 CHEMBL293332 Bioactive 3Am-6Et-8,9diMe-PBOA-5one

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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