CFam Chemical Families Database
BIDD Pharmainformatics Databases
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27482
Family Name Urokinase-type plasminogen activator and Plasminogen inhibitor 1o5c family
No. of Seeds 5 No. of Other Members 12
Family Centroid CFAMM00482839 Functional Category Bioactive
Superfamily Plasminogen and Beta-lactamase Binder Superfamily 2
Class Class 1967

Cousin Family NamesSeedsMembers
Histamine H4 receptor ligand AGN-PC-07ZG9H family 4 4
Serine/threonine-protein kinase Chk2 and Serine/threonine-prot... 1 0
Histone-arginine methyltransferase CARM1 inhibitor AGN-PC-07CR... 4 0
Urokinase-type plasminogen activator and Tissue-type plasminog... 1 4


External ID

Functional Category

Molecule Name

CFAMM00482844 CHEMBL62588 Bioactive (2Z)-6-fluoro-2-[6-oxo-5-(oxolan-2-ylmethoxy)cyclohexa-2,4-dien-1-ylidene]-1,3-dihydrobenzimidazole-5-carboximidamide
CFAMM00482841 CHEMBL416674 Bioactive (2Z)-6-fluoro-2-[5-[(1S,2S)-2-methylcyclopentyl]oxy-6-oxocyclohexa-2,4-dien-1-ylidene]-1,3-dihydrobenzimidazole-5-carboximidamide
CFAMM00482848 CHEMBL62509 Bioactive (2Z)-6-fluoro-2-[5-(4-methylcyclohexyl)oxy-6-oxocyclohexa-2,4-dien-1-ylidene]-1,3-dihydrobenzimidazole-5-carboximidamide
CFAMM00482839 CHEMBL293892 Bioactive 1o5c
CFAMM00482845 CHEMBL62807 Bioactive (2E)-6-fluoro-2-[5-[(1S,2S)-2-methylcyclohexyl]oxy-6-oxocyclohexa-2,4-dien-1-ylidene]-1,3-dihydrobenzimidazole-5-carboximidamide

Statistics of CFAM Database

CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.

How to cite our database

C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore

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