CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27484
Family Name Matrix metalloproteinase-9 and Metalloproteinase inhibitor 3 inhibitor 4-ethoxy-N-[(2S)-1-oxo-3-phenyl-1-(propan-2-ylamino)propan-2-yl]-1-(sulfanylmethyl)cyclohexane-1-carboxamide family
No. of Seeds 6 No. of Other Members 4
Family Centroid CFAMM00482867 Functional Category Bioactive
Superfamily Metalloproteinase and Matrix metalloproteinase-9 Binder Superfamily
Class Class 349

Cousin Family NamesSeedsMembers
Vasopressin V1a receptor Ligand Felypressin Family 12 820
Alpha-1B adrenergic receptor Ligand Lisdexamfetamine Family 14 443
Dipeptidyl peptidase 4 Inhibitor Denagliptin Family 24 151
Neprilysin Inhibitor Thiorphan Family 41 68
72 kDa type IV collagenase and Matrix metalloproteinase-9 Inhi... 40 87
Neuromedin-K receptor Ligand PD-157672 Family 9 37
Cathepsin B and Cathepsin S Inhibitor Ac-hphe-leu-ala-leuvsme ... 17 51
Genome polyprotein Inhibitor Acdif-ile-cha-cys Family 37 96
Aminopeptidase N Inhibitor 2-cinnamamido-n4-hexyl-n1-hydroxysu... 24 8
Matrix metalloproteinase-9 and Metalloproteinase inhibitor 3 i... 6 2
Matrix metalloproteinase-9 and Metalloproteinase inhibitor 3 i... 1 0


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00482870 CHEMBL60250 Bioactive N-[(2S)-1-(cyclohexylamino)-1-oxo-3-phenylpropan-2-yl]-4-ethoxy-1-(sulfanylmethyl)cyclohexane-1-carboxamide
CFAMM00482863 CHEMBL61610 Bioactive 4-ethoxy-N-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-1-(sulfanylmethyl)cyclohexane-1-carboxamide
CFAMM00482869 CHEMBL294088 Bioactive 4-methoxy-N-[(2S)-1-(methylamino)-1-oxo-3-phenylpropan-2-yl]-1-(sulfanylmethyl)cyclohexane-1-carboxamide
CFAMM00482867 CHEMBL418312 Bioactive 4-ethoxy-N-[(2S)-1-oxo-3-phenyl-1-(propan-2-ylamino)propan-2-yl]-1-(sulfanylmethyl)cyclohexane-1-carboxamide
CFAMM00482866 CHEMBL62156 Bioactive N-[(2S)-1-(benzylamino)-1-oxo-3-phenylpropan-2-yl]-4-ethoxy-1-(sulfanylmethyl)cyclohexane-1-carboxamide
CFAMM00482865 CHEMBL64390 Bioactive N-[(2S)-1-(cyclopentylamino)-1-oxo-3-phenylpropan-2-yl]-4-ethoxy-1-(sulfanylmethyl)cyclohexane-1-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

48711 visits since 2014 .........

 



Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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