CFam Chemical Families Database
BIDD Pharmainformatics Databases
 
   
Click on CFAM IDs and names to search or view in CFAM, click on external IDs to view the entity in its source database.

CFam Family Information

CFAM Family ID CFFBM27495
Family Name Neutrophil collagenase and Stromelysin-1 inhibitor (3R)-N-hydroxy-2-(4-morpholin-4-ylphenyl)sulfonyl-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxamide family
No. of Seeds 1 No. of Other Members 6
Family Centroid CFAMM00482917 Functional Category Bioactive with Natural Product
Superfamily Prelamin-A/C and Cyclin-dependent kinase 2 Binder Superfamily 2
Class Class 8

Cousin Family NamesSeedsMembers
5-hydroxytryptamine receptor 1B and 5-hydroxytryptamine recept... 14 2769
Growth hormone receptor Ligand EP-51216 Family 34 390
Lethal factor Inhibitor GM6001 Family 50 435
Cholecystokinin receptor type A Ligand VL-0395 Family 12 117
Kappa-type opioid receptor and Mu-type opioid receptor Ligand ... 19 108
Gamma-aminobutyric acid receptor subunit alpha-1 and Gamma-ami... 12 72
Gonadotropin-releasing hormone receptor ligand 5-[2-[[(2S)-2-[... 7 58
5-hydroxytryptamine receptor 1A and 5-hydroxytryptamine recept... 4 0
Survival motor neuron protein and Nonstructural protein 1 inhi... 1 18
Somatostatin receptor type 4 ligand methyl 5-(diaminomethylide... 2 34
cGMP-specific 3',5'-cyclic phosphodiesterase and Dual 3',5'-cy... 4 129
Substance-P receptor ligand N-[(2S)-5-[3,5-bis(trifluoromethyl... 4 6
Melanin-concentrating hormone receptor 1 and Melanin-concentra... 5 6
Substance-P receptor ligand [3,5-bis(trifluoromethyl)phenyl]-[... 17 1
Hematopoietic prostaglandin D synthase inhibitor 4-(3-methylis... 1 7
Oxytocin receptor ligand (3R,6R)-3-(2,3-dihydro-1H-inden-2-yl)... 20 2
C-C chemokine receptor type 2 ligand 2-[4-(5-amino-1H-indol-3-... 3 2
Leucine-rich repeat serine/threonine-protein kinase 2 and Vasc... 3 3
Interstitial collagenase and Matrix metalloproteinase-9 inhibi... 1 5


CFAM Mol ID

External ID

Functional Category

Molecule Name

CFAMM00482917 CHEMBL294680 Bioactive (3R)-N-hydroxy-2-(4-morpholin-4-ylphenyl)sulfonyl-1,3,4,9-tetrahydropyrido[3,4-b]indole-3-carboxamide

Statistics of CFAM Database

 
CFAM currently contains 490,279 molecules in 87,136 families, 34,880 superfamilies and 11,643 classes.
 

How to cite our database

 
C. Zhang, L. Tao, C. Qin, P. Zhang, S.Y. Chen, X. Zeng, F. Xu, Z. Chen, S.Y. Yang and Y.Z. CFam: A Chemical Families Database Based on Iterative Selection of Functional Seeds and Seed-Directed Compound Clustering. Nucl. Acids Res. 43 (D1): D558-D565 (2015) (First published online: November 20, 2014).
 

Last update by

 
2014.08.29
 

 

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Dr. Chen Yuzong

Deputy Director of Center for Computational Science and Engineering
Professor in Department of Pharmacy
National University of Singapore, Singapore


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